Intraspecific variation of Bothrops pubescens (cope, 1869) venom in Uruguay (Serpentes: Viperidae)



Título del documento: Intraspecific variation of Bothrops pubescens (cope, 1869) venom in Uruguay (Serpentes: Viperidae)
Revista: The journal of venomous animals and toxins including tropical diseases
Base de datos: PERIÓDICA
Número de sistema: 000298943
ISSN: 1678-9199
Autores: 1

Instituciones: 1Instituto de Higiene, Departamento de Desarrollo Biotecnológico y Producción, Montevideo. Uruguay
Año:
Volumen: 12
Número: 4
Paginación: 604-611
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés In Uruguay, there was no information about the variations degree in Bothrops pubescens venoms until the present work, in which we investigated intraspecific venom variation using polyacrylamide gel electrophoresis (SDS-PAGE). We found some differences in the venom protein profile; however, they were not related to the parameters studied (geographic distribution, weight, sex, and captivity time). Moreover, we distinguished two different groups in relation to band densities at 49 and 57 kDa. Specimens with predominant density in the 49kDa band tend to be predominantly females. Weight distribution in this group extended for all the range (150-1500 g) with an average weight of 720 g. The other group (57kDa predominant band) showed restricted weight range (150-400 g) with an average weight of 280 g. Cluster analysis was also performed. The variability observed in the venom profile probably corresponds to genetic variations
Disciplinas: Medicina
Palabras clave: Farmacología,
Toxicología,
Veneno de víbora,
Antivenenos,
Patrones electroforéticos,
Bothrops pubescens,
Viperidae
Keyword: Medicine,
Pharmacology,
Toxicology,
Snake venom,
Antivenoms,
Electrophoretic patterns,
Bothrops pubescens,
Viperidae
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