Viral hepatitis in patients infected with human immunodeficiency virus



Título del documento: Viral hepatitis in patients infected with human immunodeficiency virus
Revista: The brazilian journal of infectious diseases
Base de datos: PERIÓDICA
Número de sistema: 000290755
ISSN: 1413-8670
Autores: 1
2
3


Instituciones: 1Universidade Estadual de Campinas, Hospital das Clinicas, Campinas, Sao Paulo. Brasil
2Universidade Estadual de Campinas, Faculdade de Medicina, Campinas, Sao Paulo. Brasil
3Universidade Estadual de Campinas, Centro de Hematologia e Hemoterapia, Campinas, Sao Paulo. Brasil
Año:
Periodo: Ago
Volumen: 7
Número: 4
Paginación: 253-261
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, analítico
Resumen en inglés ABSTRACT From 1992 to 1995 we studied 232 (69% male, 87% Caucasian) anti-human immunodeficiency virus (anti-HIV) positive Brazilian patients, through a questionnaire; HIV had been acquired sexually by 50%, from blood by 32%, sexually and/or from blood by 16.4% and by an unknown route by 1.7%. Intravenous drug use was reported by 29%; it was the most important risk factor for HIV transmission. The alanine aminotransferase quotient (qALT) was >1 for 40% of the patients, 93.6% had anti-hepatitis A virus antibody, 5.3% presented hepatitis B surface antigen, 44% were anti-hepatitis B core antigen positive and 53.8% were anti-hepatitis C virus (anti-HCV) positive. The anti-HCV test showed a significant association with qALT>1. Patients for whom the probable HIV transmission route was blood had a 10.8 times greater risk of being anti-HCV positive than patients infected by other routes. Among 30 patients submitted to liver biopsy, 18 presented chronic hepatitis
Disciplinas: Biología
Palabras clave: Inmunología,
Virus,
Diagnóstico,
Virus de la hepatitis C,
VIH,
Alanina aminotransferasa,
Anti-anticuerpos de la hepatitis A,
Antígeno de superficie de la hepatitis B,
Anti-hepatitis B
Keyword: Biology,
Immunology,
Virus,
Hepatitis C virus,
HIV,
Alanine aminotransferase,
Anti-hepatitis A antibody,
Hepatitis B surface antigen,
Anti-hepatitis B core antigen,
Diagnosis
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