Two family members with a syndrome of headache and rash caused by human parvovirus B19



Título del documento: Two family members with a syndrome of headache and rash caused by human parvovirus B19
Revista: The brazilian journal of infectious diseases
Base de datos: PERIÓDICA
Número de sistema: 000290670
ISSN: 1413-8670
Autores: 1
2
3

4
Instituciones: 1Hospital Universitario Antonio Pedro, Departamento de Doencas Infecciosas, Niteroi, Rio de Janeiro. Brasil
2Universidade Federal Fluminense, Hospital Universitario Antonio Pedro, Niteroi, Rio de Janeiro. Brasil
3Universidade Federal Fluminense, Instituto Biomedico, Niteroi, Rio de Janeiro. Brasil
4Fundacao Oswaldo Cruz, Bio-Manguinhos, Rio de Janeiro. Brasil
Año:
Periodo: Feb
Volumen: 5
Número: 1
Paginación: 37-39
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, analítico
Resumen en inglés Human parvovirus B19 infection can cause erythema infectiosum (EI) and several other clinical presentations. Central nervous system (CNS) involvement is rare, and only a few reports of encephalitis and aseptic meningitis have been published. Here, we describe 2 cases of B19 infection in a family presenting different clinical features. A 30 year old female with a 7-day history of headache, malaise, myalgias, joint pains, and rash was seen. Physical examination revealed a maculopapular rash on the patient's body, and arthritis of the hands. She completely recovered in 1 week. Two days before, her 6 year old son had been admitted to a clinic with a 1-day history of fever, headache, abdominal pain and vomiting. On admission, he was alert, and physical examination revealed neck stiffness, Kerning and Brudzinski signs, and a petechial rash on his trunk and extremities. Cerebrospinal fluid analysis was normal. He completely recovered in 5 days. Acute and convalescent sera of both patients were positive for specific IgM antibody to B19. Human parvovirus B19 should be considered in the differential diagnosis of aseptic meningitis, particularly during outbreaks of erythema infectiosum. The disease may mimic meningococcemia and bacterial meningitis
Disciplinas: Biología,
Medicina
Palabras clave: Virus,
Microbiología,
Neurología,
Parvovirus humano B19,
Meningitis aséptica,
Erythema infectiosum
Keyword: Biology,
Medicine,
Virus,
Microbiology,
Neurology,
Human parvovirus B19,
Aseptic meningitis,
Erythema infectiosum
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