| Revista: | The brazilian journal of infectious diseases |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000291034 |
| ISSN: | 1413-8670 |
| Autores: | Mattos, Ivo Gomes de1 Ribeiro, Marta Osorio2 Netto, Isabel Cristina de O3 D'Azevedo, Pedro Alves4 |
| Instituciones: | 1Fundacao Universidade Federal do Rio Grande, Departamento de Patologia, Rio Grande, Rio Grande do Sul. Brasil 2Secretaria de Saude, Laboratorio Central de Bioquimica, 3Fundacao Universidade Federal do Rio Grande, Departamento de Medicina, Rio Grande, Rio Grande do Sul. Brasil 4Fundacao Faculdade Federal de Ciencias Medicas de Porto Alegre, Porto Alegre, Rio Grande do Sul. Brasil |
| Año: | 2006 |
| Periodo: | Jun |
| Volumen: | 10 |
| Número: | 3 |
| Paginación: | 194-198 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Nota breve o noticia |
| Enfoque: | Caso clínico |
| Resumen en inglés | Tuberculosis is an increasingly important public health problem in developing countries. We studied 111 tuberculosis patients confirmed by mycobacteria isolation between 1998 and 2000 in Rio Grande, in south Brazil. One-hundred-thirteen pulmonary and extrapulmonary clinical materials were examined through culture by the Ogawa-Kudoh method and through smear examination by the Ziehl-Nielsen or Kinyoun methods. The identification of Mycobacterium tuberculosis was done through the usual phenotypical methods. The proportion method (indirect technique) was used to determine the resistance of isolates. The man/woman ratio was 2.6:1, 75% were white, and the group had a mean age of 39.7±12.7. Risk factors were present in 38.7% (34 men and 9 women, p=0.2), with a mean age of 35 (p=0.002); infection by HIV was the most frequent (28.8%), followed by alcoholism (16.2%) and injected drug use (15.3%). The frequency of M. tuberculosis isolates was 99.1%. Pulmonary disease occurred in 88.3% of the cases, extrapulmonary in 9.9% and 1.8% in both. There was an association between extrapulmonary tuberculosis and the presence of risk factors (p=0.0001). Resistance to isoniazid was found in 4% of the isolates and to isoniazid and rifampin in 2%, all being patients with some risk factors. The profile of tuberculosis in the population of this study followed the pattern described for developing regions of the world |
| Disciplinas: | Medicina |
| Palabras clave: | Microbiología, Neumología, Inmunología, Resistencia, Tuberculosis, Mycobacterium tuberculosis |
| Keyword: | Medicine, Microbiology, Pneumology, Tuberculosis, Mycobacterium tuberculosis, Immunology, Resistance |
| Texto completo: | Texto completo (Ver HTML) |
