Nasopharyngeal colonization and penicillin resistance among pneumococcal strains: a Worldwide 2004 update



Título del documento: Nasopharyngeal colonization and penicillin resistance among pneumococcal strains: a Worldwide 2004 update
Revista: The brazilian journal of infectious diseases
Base de datos: PERIÓDICA
Número de sistema: 000290972
ISSN: 1413-8670
Autores: 1

2
Instituciones: 1Universidade Federal da Bahia, Faculdade de Medicina, Salvador, Bahia. Brasil
2Universidade Federal da Bahia, Faculdade de Bioquimica, Salvador, Bahia. Brasil
Año:
Periodo: Ago
Volumen: 10
Número: 4
Paginación: 293-303
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Surveillance of nasopharyngeal pneumococcus has proven to be a valuable tool for the monitoring of antibiotic resistance. We reviewed the latest information on colonization rate and penicillin resistance by making a MEDLINE search, using the terms "nasopharyngeal carriage" and "Streptococcus pneumoniae". Out of 225 articles found, data from 109 recent publications (89% from 1996-2003) were analyzed. Data were reported from 41 countries of six continents. Individuals under the age of five (64.3%) or 10 years (85.7%) were enrolled, including children attending day-care centers (32.1%) or orphanages (3.6%), and healthy individuals (78.6%) or sick patients (43.6%); biological samples were collected mainly by nasopharyngeal swabs (89.3%). The highest colonization rates were reported from Africa (85-87.2%), where several authors did not find high rates of penicillin resistance. On the other hand, studies conducted in North and Central America reported high-level penicillin resistance at rates of approximately 20-30%. Great variation in the rates of pneumococcal colonization and penicillin resistance were observed within regions or continents. There were also considerable differences in similar populations located in different areas of the same country. Data regarding pneumococcal colonization and penicillin resistance are not available from most countries. We also examined the use of antibiotics to treat pneumococcal infections
Disciplinas: Biología,
Medicina
Palabras clave: Bacterias,
Farmacología,
Microbiología,
Streptococcus pneumoniae,
Portador nasofaríngeo,
Resistencia a fármacos,
Penicilina
Keyword: Biology,
Medicine,
Bacteria,
Microbiology,
Pharmacology,
Streptococcus pneumoniae,
Nasopharyngeal carrier,
Drug resistance,
Penicillin
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