blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil



Título del documento: blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil
Revista: The brazilian journal of infectious diseases
Base de datos: PERIÓDICA
Número de sistema: 000290983
ISSN: 1413-8670
Autores: 1

2
Instituciones: 1Universidade Federal do Rio de Janeiro, Instituto de Microbiologia "Paulo de Goes", Rio de Janeiro. Brasil
2School of Public Health, Infectious Diseases Section, Berkeley, California. Estados Unidos de América
Año:
Periodo: Ago
Volumen: 10
Número: 4
Paginación: 251-253
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en inglés Previous analysis of Pseudomonas aeruginosa class-1 integrons from Rio de Janeiro, Brazil, revealed the blaGES gene in one isolate. We screened isolates of two widespread PFGE genotypes, A and B, at a public hospital in Rio, for the presence of blaGES. The gene was detected in all seven P. aeruginosa isolates belonging to genotype B. Three of the seven genotype-B isolates were resistant to amikacin, aztreonam, ceftazidime, cefepime, ciprofloxacin, gentamicin, imipenem, meropenem, piperacillin-tazobactam and ticarcillin-clavulanic acid. The other four isolates were resistant to all these agents, except gentamicin, imipenem, meropenem and piperacillin-tazobactam. A synergistic effect between ceftazidime and imipenem or clavulanic acid suggested the production of GES-type ESBL
Disciplinas: Biología,
Química
Palabras clave: Bacterias,
Bioquímica,
Química farmacéutica,
Pseudomonas aeruginosa,
Antibióticos,
BlaGES,
Hospitales públicos,
Rio de Janeiro,
Brasil
Keyword: Biology,
Chemistry,
Bacteria,
Biochemistry,
Medicinal chemistry,
Pseudomonas aeruginosa,
Antibiotics,
BlaGES,
Public hospitals,
Rio de Janeiro,
Brazil
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