Bartonelosis (Carrion's Disease) in the pediatric population of Peru: an overview and update



Título del documento: Bartonelosis (Carrion's Disease) in the pediatric population of Peru: an overview and update
Revista: The brazilian journal of infectious diseases
Base de datos: PERIÓDICA
Número de sistema: 000290856
ISSN: 1413-8670
Autores: 1

2

3
Instituciones: 1Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Lima. Perú
2University of Illinois at Chicago, Chicago, Illinois. Estados Unidos de América
3Ministerio de Salud, Lima. Perú
Año:
Periodo: Oct
Volumen: 8
Número: 5
Paginación: 331-339
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico
Resumen en inglés Bartonellosis, or Carrion's Disease, is an endemic and reemerging disease in Peru and Ecuador. Carrion's Disease constitutes a health problem in Peru because its epidemiology has been changing, and it is affecting new areas between the highland and the jungle. During the latest outbreaks, and previously in endemic areas, the pediatric population has been the most commonly affected. In the pediatric population, the acute phase symptoms are fever, anorexia, malaise, nausea and/or vomiting. The main signs are pallor, hepatomegaly, lymphadenopathies, cardiac murmur, and jaundice. Arthralgias and weight loss have also commonly been described. The morbidity and mortality of the acute phase is variable, and it is due mainly to superimposed infections or associated respiratory, cardiovascular, neurological or gastrointestinal complications. The eruptive phase, also known as Peruvian Wart, is characterized by eruptive nodes (which commonly bleed) and arthralgias. The mortality of the eruptive phase is currently extremely low. The diagnosis is still based on blood culture and direct observation of the bacilli in a blood smear. In the chronic phase, the diagnosis is based on biopsy or serologic assays. There are nationally standardized treatments for the acute phase, which consist of ciprofloxacin, and alternatively chloramphenicol plus penicillin G. However, most of the treatments are based on evidence from reported cases. During the eruptive phase the recommended treatment is rifampin, and alternatively, azithromycin or erythromycin
Disciplinas: Medicina
Palabras clave: Diagnóstico,
Microbiología,
Pediatría,
Bartonelosis,
Carrion's disease
Keyword: Medicine,
Diagnosis,
Microbiology,
Pediatrics,
Bartonellosis,
Carrion disease
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