| Revista: | Revista médica de Chile |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000448940 |
| ISSN: | 0034-9887 |
| Autores: | Ramírez Guerrero, Gonzalo1 Müller Ortiz, Hans2 Jara Vilugrón, Fernando1 Pedreros Rosales, Cristian1 Vera Calzaretta, Aldo3 González Burboa, Alexis1 Silva, Juan Pablo1 Torres Cifuentes, Vicente4 Villagrán Cortés, Francisco4 |
| Instituciones: | 1Universidad de Concepción, Facultad de Medicina, Concepción. Chile 2Hospital Las Higueras, Unidad de Nefrología, Diálisis y Trasplante, Talcahuano, Concepción. Chile 3Universidad de Atacama, Facultad de Ciencias de la Salud, Copiapó. Chile 4Hospital Carlos Van Buren, Unidad de Diálisis y Trasplante Renal, Valparaíso. Chile |
| Año: | 2022 |
| Volumen: | 150 |
| Número: | 2 |
| Paginación: | 147-153 |
| País: | Chile |
| Idioma: | Español |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Therapeutic Plasma Exchange (TPE) is a procedure in which plasma and harmful macromolecules are separated from the rest of the blood components by centrifugation or filtration through membranes and are replaced with solutions with albumin and/or plasma. Aim: To communicate our experience using TPE by filtration. Material and Methods: Review of records of 655 TPE sessions performed in 102 patients aged 50 ± 18 years (64% women). The requirement of renal replacement therapy (RRT) and seven days and one year mortality were recorded. Results: Forty five percent of patients had hypertension or diabetes. The main indications for TPE were pulmonary-renal syndrome (PRS) (62%) and antibody mediated graft rejection (29%), followed by neurological diseases (36%). Fifteen percent of patients required RRT for one year. Mortality at seven days and one year was 20 and 30%, respectively. Out of the total of deaths associated with kidney diseases, 88% corresponded to PRS and ANCA vasculitis. The main complications were thrombocytopenia in 41%, hypocalcemia in 18%, and hypotension in 16%. Conclusions: In our experience, TPE by filtration is a safe technique, with mild and preventable complications. Despite this, the reported mortality is high, which reflects the severity of the diseases that motivated the indication for TPE |
| Disciplinas: | Medicina |
| Palabras clave: | Inmunología, Hematología, Enfermedades autoinmunes, Intercambio de plasma, Filtración de plasma, Vasculitis |
| Keyword: | Immunology, Hematology, Autoimmune diseases, Plasma exchange, Plasma filtration, Vasculitis |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
