| Revista: | Revista médica de Chile |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000449370 |
| ISSN: | 0034-9887 |
| Autores: | Saldías Peñafiel, Fernando1 Peñaloza Tapia, Alejandro1 Farías Nesvadba, Daniela1 Farcas Oksenberg, Katia1 Reyes Sánchez, Antonia1 Cortés Meza, Josefina1 Urzúa Canales, Pablo1 Lara Hernández, Bárbara1 Aguilera Fuenzalida, Pablo1 Leiva Rodríguez, Isabel1 |
| Instituciones: | 1Pontificia Universidad Católica de Chile, Facultad de Medicina, Santiago de Chile. Chile |
| Año: | 2021 |
| Periodo: | Ago |
| Volumen: | 149 |
| Número: | 8 |
| Paginación: | 1107-1118 |
| País: | Chile |
| Idioma: | Español |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | COVID-19 is a serious public health problem worldwide. Aim: To describe the clinical features of COVID-19 infection in adult patients consulting at an Emergency Service. Material and Methods: Descriptive prospective study of adult patients with suspected COVID-19 consulting between April 1 and July 31, 2020, at the Emergency Service of a clinical hospital. Clinical features, chronic comorbidities and demographic data were recorded. Results: We assessed 2,958 adult patients aged 42 ± 15 years (46% males). In 54% of them, COVID-19 infection was confirmed, 40% had preexisting diseases, especially hypertension (15%), hypothyroidism (6%), diabetes (6%), asthma (5%) and obesity (6%). The main clinical manifestations associated with COVID-19 were general malaise (79%), anorexia (38%), myalgia (64%), fever (52%), headache (70%), anosmia/dysgeusia (60%), cough (56%), dyspnea (54%) and diarrhea (36%). In the multivariate analysis, the main clinical predictors of COVID-19 infection were malaise, anorexia, fever, myalgia, headache, nasal congestion, cough, expectoration, anosmia/dysgeusia, and history of close contact with a SARS-CoV-2 patient. Odynophagia and chest discomfort were negative predictors of the disease. The history of fever associated with anorexia, cough, and dyspnea or anosmia/dysgeusia and close contact with a SARS-CoV-2 patient had high specificity and positive predictive value for COVID-19 infection. Conclusions: Clinical features of COVID-19 infection were highly unspecific in these patients. Clinical diagnostic prediction models could be useful to support healthcare decision making at primary care setting |
| Disciplinas: | Medicina |
| Palabras clave: | Neumología, Virus, Diagnóstico, COVID-19, Infecciones respiratorias, Factores pronósticos, Factores de riesgo |
| Keyword: | Pneumology, Virus, Diagnosis, COVID-19, Respiratory infections, Prognostic factors, Risk factors |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
