| Revista: | Revista de saude publica |
| Base de datos: | |
| Número de sistema: | 000535943 |
| ISSN: | 0034-8910 |
| Autores: | Rod, J.E.1 Oviedo Trespalacios, Oscar2 Cortes Ramirez, Javier1 |
| Instituciones: | 1Queensland University of Technology, School of Public Health and Social Work, Brisbane, Queensland. Australia 2Queensland University of Technology, Institute of Health and Biomedical Innovation, Brisbane, Queensland. Australia 3Queensland University of Technology, Centre for Accident Research and Road Safety Queensland, Brisbane, Queensland. Australia 4Universidad del Norte, Departamento de ingeniería, Barranquila, Atlántico. Colombia |
| Año: | 2020 |
| Volumen: | 54 |
| País: | Brasil |
| Idioma: | Inglés |
| Resumen en inglés | The World Health Organization has emphasized that one of the most important questions to address regarding the covid-19 pandemic is to understand risk factors for disease severity. We conducted a brief review that synthesizes the available evidence and provides a judgment on the consistency of the association between risk factors and a composite end-point of severe-fatal covid-19. Additionally, we also conducted a comparability analysis of risk factors across 17 studies. We found evidence supporting a total of 60 predictors for disease severity, of which seven were deemed of high consistency, 40 of medium and 13 of low. Among the factors with high consistency of association, we found age, C-reactive protein, D-dimer, albumin, body temperature, SOFA score and diabetes. The results suggest that diabetes might be the most consistent comorbidity predicting disease severity and that future research should carefully consider the comparability of reporting cases, factors, and outcomes along the different stages of the natural history of covid-19. |
| Keyword: | Coronavirus Infections, epidemiology, Fatal Outcome, Risk Factors, Review |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
