Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes



Título del documento: Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes
Revista: Revista brasileira de hematologia e hemoterapia
Base de datos: PERIÓDICA
Número de sistema: 000306159
ISSN: 1516-8484
Autores: 1
1
Instituciones: 1Universidade Estadual Paulista "Julio de Mesquita Filho", Instituto de Biociencias, Letras e Ciencias Exatas, Sao Paulo. Brasil
Año:
Periodo: Ene-Mar
Volumen: 28
Número: 1
Paginación: 65-67
País: Brasil
Idioma: Portugués
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en inglés Among the electrophoretical methodologies for hemoglobin examinations under different experimental conditions, isoelectrofocusing and high performance liquid chromatography are the most frequently used for the detection of hemoglobin variants. Moreover, molecular techniques are also developed in many laboratories. The correct laboratorial diagnosis of hemoglobin alterations is especially important for the interactive forms principally in Brazil, because of the many associations of hemoglobin alterations and variants with co-migration. The association of classical and molecular techniques is essential for accurate identification of hemoglobin variants
Disciplinas: Medicina
Palabras clave: Diagnóstico,
Hematología,
Hemoglobinopatías,
Variantes,
Polimorfismo
Keyword: Medicine,
Diagnosis,
Hematology,
Hemoglobinopathies,
Variants,
Polymorphism
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