| Revista: | Quimica nova |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000313216 |
| ISSN: | 0100-4042 |
| Autores: | Azevedo, Mariangela S1 Alves, Ana Paula L Alves, Glaucia B.C Cardoso, Jari N Lopes, Rosangela S.C Lopes, Claudio C |
| Instituciones: | 1Universidade Federal do Rio de Janeiro, Instituto de Quimica, Rio de Janeiro. Brasil |
| Año: | 2006 |
| Periodo: | Nov |
| Volumen: | 29 |
| Número: | 6 |
| Paginación: | 1259-1265 |
| País: | Brasil |
| Idioma: | Portugués |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | alpha-Bromoacetophenones are important in organic synthesis. They have been widely used as precursors of several natural products. Several methods of bromination aiming at their synthesis have been described, however they furnish a mixture of starting material 10, mono 8 and dibromide 11 products. We developed a novel, simple and efficient synthesis of these compounds with applications in the synthesis of benzoylbenzofurans 9, compounds with important pharmacological properties, such as the ability of dilating the coronary artery and analgesic action. Such compounds have also been used as key intermediates to obtain quinone systems |
| Disciplinas: | Química |
| Palabras clave: | Química orgánica, Alfa-bromocetofenonas, Síntesis orgánica, Benzoilbenzofuranos, Tribromuro de feniltrimetilamonio |
| Keyword: | Chemistry, Organic chemistry, Alpha-bromoacetophenones, Organic synthesis, Benzoylbenzofurans, Phenyltrimethylammonium tribromide |
| Texto completo: | Texto completo (Ver HTML) |
