Antioxidantes dietéticos: controvérsias e perspectivas



Título del documento: Antioxidantes dietéticos: controvérsias e perspectivas
Revista: Quimica nova
Base de datos: PERIÓDICA
Número de sistema: 000313420
ISSN: 0100-4042
Autores: 1

Instituciones: 1Universidade de Sao Paulo, Instituto de Quimica, Sao Paulo. Brasil
Año:
Periodo: Abr
Volumen: 30
Número: 2
Paginación: 441-449
País: Brasil
Idioma: Portugués
Tipo de documento: Artículo
Enfoque: Descriptivo, divulgación
Resumen en inglés The generation of reactive oxygen and nitrogen species (ROS and RNS) during metabolism is capable of damaging cellular biomolecules. To be protected against oxidative injury, cells evolved complex cellular defense mechanisms and the capability to use exogenous antioxidants to eliminate ROS/RNS. The potential role of micronutrients as antioxidants (vitamin C, vitamin E, carotenoids and poliphenols) has stimulated intense research efforts. In various human supplementation studies, however, these compounds presented pro-oxidant effects at high doses for most risk groups. Therefore, more studies about the bioavailability, tissue uptake, metabolism and biological activities should be performed before establishing recommendations for disease prevention
Disciplinas: Química
Palabras clave: Química farmacéutica,
Vitaminas antioxidantes,
Carotenoides,
Polifenoles
Keyword: Chemistry,
Medicinal chemistry,
Antioxidant vitamins,
Carotenoids,
Polyphenols
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