Is there correlation between the turbulent eddies size and mechanical hemolysis ?
Título del documento: Is there correlation between the turbulent eddies size and mechanical hemolysis ?
Revista: Journal of the Brazilian Society of Mechanical Sciences
Base de datos: PERIÓDICA
Número de sistema: 000312042
ISSN: 0100-7386
Autores: 1
Instituciones: 1Universidade Federal de Minas Gerais, Departamento de Engenharia Mecanica, Belo Horizonte, Minas Gerais. Brasil
Año:
Volumen: 22
Número: 4
Paginación: 565-569
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en inglés Hemolytic profile of an artificial device chronically implanted in the cardiovascular system may represent the difference between the success and failure in its long-term performance. Last decades have witnessed efforts on the development of methods capable of predicting red blood cell damage in artificial organs. However, all of them have had limited success to predict hemolysis. The primary cause of this problem is that such models do not take into consideration structures of turbulent flow. The present paper demonstrates that microscopic measurable occurrences of the turbulent flow may be linked to red blood cell trauma. This study suggests that if the smallest turbulent eddies dimension is under 10 m m hemolysis is not dependent on the exposure time and the red blood cells damage depends only on the dissipation of the turbulent energy in the erythrocyte membrane. The analysis reported here opens the possibility of mapping the flow field in artificial assist devices based on the smallest eddy length scales. This is a promising new trend and should be considered in the designing requirements of the next generations of artificial organs
Disciplinas: Física y astronomía,
Medicina
Palabras clave: Dinámica de fluidos,
Sistema cardiovascular,
Hemólisis,
Sangre,
Flujo,
Turbulencia,
Organos artificiales,
Daño
Keyword: Physics and astronomy,
Medicine,
Fluid dynamics,
Cardiovascular system,
Hemolysis,
Blood,
Flow,
Turbulence,
Artificial organs,
Damage
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