| Revista: | International braz j urol |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000434776 |
| ISSN: | 1677-5538 |
| Autores: | Canat, Lütfi1 Degirmentepe, Recep Burak1 Atalay, Hasan Anil1 Çakir, Suleyman Sami1 Alkan, Ilter1 Çulha, Mehmet Gokhan1 Ozbir, Sait1 Canat, Masum2 |
| Instituciones: | 1Okmeydani Training and Research Hospital, Department of Urology, Estambul. Turquía 2Sisli Etfal Training and Research Hospital, Department of Endocrinology and Metabolism, Estambul. Turquía |
| Año: | 2019 |
| Periodo: | May-Jun |
| Volumen: | 45 |
| Número: | 3 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Purpose: To investigate the relationship between 25-hydroxyvitamin D (25 (OH) D) levels and acquired premature ejaculation (PE). Materials and Methods: A total of 97 patients with acquired PE and 64 healthy men as a control group selected from volunteers without PE attending our Andrology Outpatient Clinic between November 2016 and April 2017 were included the study. All patients were considered to have acquired PE if they fulfilled the criteria of the second Ad Hoc International Society for Sexual Medicine Committee. Premature ejaculation diagnostic tool questionnaires were used to assessment of PE and all participants were instructed to record intravaginal ejaculatory latency time. Vitamin D levels were evaluated in all participants using high performance liquid chromatography method included in the study. Results: Compared to men without PE, the patients with acquired PE had significantly lower 25 (OH) D levels (12.0 ± 4.5 ng/mL vs. 18.2 ± 7.4 ng/mL, p < 0.001). In the logistic regression analysis, 25 (OH) D was found to be an independent risk factor for acquired PE, with estimated odds ratios (95% CI) of 0.639 (0.460-0.887, p = 0.007) and the area under curve of the ROC curve of 25 (OH) D diagnosing acquired PE was 0.770 (95% CI: 0.695 to 0.844, p < 0.001). The best cut-off value was 16 ng/mL with a sensitivity of 60.9%, specificity of 83.5%, PPV of 70.9%, and NPV of 76.4% to indicate acquired PE. Conclusions: This study demonstrates that lower vitamin D levels are associated with the acquired PE. The result of our study showed that the role of serum vitamin D levels should be investigate in the etiology of acquired PE. Perhaps supplementation of vitamin D in men with acquired PE will ameliorate the sexual health of these patients |
| Disciplinas: | Medicina |
| Palabras clave: | Endocrinología, Urología, Hormonas esteroides, Vitamina D, Eyaculación precoz |
| Keyword: | Endocrinology, Urology, Steroid hormones, Premature ejaculation, Vitamin D |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
