| Revista: | International braz j urol |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000296950 |
| ISSN: | 1677-5538 |
| Autores: | Barros, Milton1 Martinelli, Reinaldo Rocha, Heonir |
| Instituciones: | 1Universidade Federal da Bahia, Escola de Medicina, Salvador, Bahia. Brasil |
| Año: | 2006 |
| Periodo: | May-Jun |
| Volumen: | 32 |
| Número: | 3 |
| Paginación: | 350-354 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, analítico |
| Resumen en inglés | OBJECTIVE: The present study aims at assessing the occurrence of pyelonephritis and long-term complications in rats submitted to surgical reduction of bladder capacity. MATERIALS AND METHODS: Sprague-Dawley rats were submitted to supratrigonal cystectomy (29 animals) or sham operation (15 animals) and sacrificed 2, 4 and 6 months after the surgical procedure. The arterial blood pressure and serum creatinine levels were assessed before the surgery and at the time of the sacrifice. After the sacrifice a careful inspection of the urinary apparatus was performed to the characterization of the hydronephrosis and for the detection of the presence of calculi. With sterile technique, the urine was aspirated from the bladder and the kidneys removed and sent to a microbiologic study. RESULTS: Pyelonephritis was frequent in animals submitted to supratrigonal cystectomy. The most frequent and isolated microorganisms were Staphylococcus sp. and E. coli. The presence of urinary calculi was correlated significantly to the presence of urinary tract infection (p < 0.003). Arterial hypertension was frequent amongst animals submitted to supratrigonal cystectomy. Serum creatinine was high in 72.4% of the animals in the group submitted to supratrigonal cystectomy. The presence of calculi and pyelonephritis were frequent in rats presenting renal insufficiency and in hypertensive rats. CONCLUSIONS: The long-term course of urinary infection in rats submitted to supratrigonal cystectomy was characterized by a high incidence of renal insufficiency and ar |
| Disciplinas: | Medicina |
| Palabras clave: | Cirugía, Medicina experimental, Pielonefritis, Ratas, Cistectomía, Litiasis |
| Keyword: | Medicine, Experimental medicine, Surgery, Pyelonephritis, Rats, Cystectomy, Lithiasis |
| Texto completo: | Texto completo (Ver HTML) |
