Assessment of serum level of prostate-specific antigen adjusted for the transition zone volume in early detection of prostate cancer



Título del documento: Assessment of serum level of prostate-specific antigen adjusted for the transition zone volume in early detection of prostate cancer
Revista: International braz j urol
Base de datos: PERIÓDICA
Número de sistema: 000296766
ISSN: 1677-5538
Autores: 1
Instituciones: 1Universidade Federal do Rio Grande do Sul, Hospital Geral de Porto Alegre, Porto Alegre, Rio Grande do Sul. Brasil
Año:
Periodo: Mar-Abr
Volumen: 31
Número: 2
Paginación: 137-146
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, analítico
Resumen en inglés On the other hand, when F/T PSA was used, the loss would reach almost 40%; however less than 30% would undergo unnecessary biopsies. Nevertheless, PSADTZ had the only AUC presenting p < 0.05 in significance when compared with 50%, and was consequently discriminative. CONCLUSIONS: PSADTZ increased PSA specificity in early detection of PCa in males with PSA between 4.0 and 10 ng/mL. However, it was shown to have lower predictive value and lower accuracy than the percentage of free PSA since it presents a higher negative predictive value than all other parameters assessed, and it can be considered clinically useful for reducing unnecessary indications for biopsy
Disciplinas: Medicina
Palabras clave: Cirugía,
Diagnóstico,
Oncología,
Neoplasias,
Próstata,
Antígeno prostático específico,
Clasificación
Keyword: Medicine,
Diagnosis,
Oncology,
Surgery,
Neoplasms,
Prostate,
Prostate specific antigen,
Classification
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