Improved growth model for two-stage continuous cultures of Lactobacillus helveticus



Título del documento: Improved growth model for two-stage continuous cultures of Lactobacillus helveticus
Revista: Electronic journal of biotechnology
Base de datos: PERIÓDICA
Número de sistema: 000336081
ISSN: 0717-3458
Autores: 1
2
2
2
Instituciones: 1Universite Ferhat Abbas, Faculte des Sciences de l’Ingenieur, Setif. Argelia
2Universite de Rennes, Ecole Nationale Superieure de Chimie de Rennes, Rennes, Ille-et-Vilaine. Francia
Año:
Periodo: Sep
Volumen: 13
Número: 5
País: Chile
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés An unstructured model for growth and lactic acid production during two-stage continuous cultures of Lactobacillus helveticus was previously developed. The Verlhust model was considered to describe growth kinetics. Production models was based on modified Luedeking-Piret expressions involving an inhibitory effect for the first stage (seed culture) and a nutritional limitation effect for the second stage (culture). To account for the decrease of the biomass concentration observed in the second stage, the dilution rate Dc was replaced by an exponential term of the dilution rate in the growth and product relations. Contrarily to the previous model, the important decrease of the biomass concentration observed at steady state in the second stage at high dilution rates, namely close to wash out, was correctly described by the new model. It also proved to satisfactory describes production data and volumetric productivity
Disciplinas: Biología
Palabras clave: Biotecnología,
Fermentación,
Cultivo continuo,
Limitación de sustrato,
Acido láctico,
Cinética de crecimiento,
Lactobacillus helveticus
Keyword: Biology,
Biotechnology,
Fermentation,
Continuous culture,
Substrate limitation,
Lactic acid,
Growth kinetics,
Lactobacillus helveticus
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