Recent advances in the use of Langmuir monolayers as cell membrane models



Título del documento: Recent advances in the use of Langmuir monolayers as cell membrane models
Revista: Ecletica quimica
Base de datos:
Número de sistema: 000552519
ISSN: 0100-4670
Autores: 1
1
Instituciones: 1University of São Paulo, São Carlos Institute of Physics, São Carlos, Brazil.,
Año:
Volumen: 46
Paginación: 18-29
País: Brasil
Idioma: Inglés
Resumen en inglés Understanding the role of biomolecules in cells at the molecular level has been the trade of Prof. Marcio Francisco Colombo and Prof. João Ruggiero Neto in their carriers, which is why it was found appropriate to address the use of Langmuir monolayers as cell membrane models in this special issue. In the review paper, we elaborate upon the reasons why Langmuir monolayers are good models with the possible control of membrane composition and molecular packing. After describing several experimental methods to characterize the Langmuir monolayers, we discuss selected results from the last five years where monolayers were made to interact with pharmaceutical drugs, emerging pollutants and other biologically-relevant molecules. The challenges to take the field forward are also commented upon.
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