Revista: | Brazilian journal of physics |
Base de datos: | PERIÓDICA |
Número de sistema: | 000398966 |
ISSN: | 0103-9733 |
Autores: | Oliveira, Cristiano L.P1 Monteiro, Andrea M1 Neto, Antonio M. Figueiredo1 |
Instituciones: | 1Universidade de Sao Paulo, Instituto de Fisica, Sao Paulo. Brasil |
Año: | 2014 |
Periodo: | Dic |
Volumen: | 44 |
Número: | 6 |
Paginación: | 753-764 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Analítico |
Resumen en inglés | This work presents a systematic study of lowdensity lipoprotein (LDL) in solutions subjected to subtle temperature changes, monitored by small angle X-ray scattering. From the data analysis, information about the equilibrium aggregation of the particles, as well as changes on the internal structure of the lipoproteins, were observed. The electron density profiles of the LDL particles were retrieved with a recently developed deconvolution method. Our results indicate that LDL particles keep their structure in the temperature range from about 22 °C up to 60 °C. Moreover, the formation of aggregates and their evolution as a function of time were monitored. Interestingly, when the temperature is raised to 80 °C, the results indicate the rupture of the particle and unspecific aggregation |
Disciplinas: | Física y astronomía |
Palabras clave: | Física, Lipoproteínas, Lipoproteínas de baja densidad |
Keyword: | Physics and astronomy, Physics, Lipoproteins, Low density lipoproteins |
Texto completo: | Texto completo (Ver PDF) |