| Revista: | Brazilian Journal of Pharmaceutical Sciences |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000451914 |
| ISSN: | 1984-8250 |
| Autores: | Forgerini, Marcela1 Lucchetta, Rosa Camila2 Oliveira, Fernanda Mariana1 Herdeiro, Maria Teresa3 Capela, Marisa Veiga4 Mastroianni, Patrícia de Carvalho1 |
| Instituciones: | 1Universidade Estadual Paulista "Julio de Mesquita Filho", Faculdade de Ciencias Farmaceuticas, Araraquara, Sao Paulo. Brasil 2Universidade Federal do Parana, Curitiba, Parana. Brasil 3Universidade de Aveiro, Instituto de Biomedicina, Aveiro. Portugal 4Universidade Estadual Paulista "Julio de Mesquita Filho", Departamento de Fisica e Quimica, Araraquara, Sao Paulo. Brasil |
| Año: | 2022 |
| Volumen: | 58 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | To assess the therapy relative to indication, effectiveness, safety and adherence in patients with Alzheimer’s disease (AD). An interventional, prospective, non-randomized study was conducted in a single secondary care center in Brazil. The pharmacist-led medication therapy management (MTM) was conducted to detect drug-related problems (DRPs) at baseline and after six months of intervention. The health status outcomes (i.e. cognitive screening tests; levels of glucose; total cholesterol; triglycerides; thyroid stimulating hormone; serum free thyroxine and blood pressure) were measured. 66 patients with AD were included, of whom 55 patients completed the follow-up of six months. 36 patients (36/55) were non-adherent to AD drug therapy. Out of detected 166 DRPs, 116 were solved. Four patients were withdrawn from the AD protocol due to resolution of prodromal symptoms. On the conclusion of the study, the MTM improved and controlled blood pressure, glucose, total cholesterol, triglycerides levels (p<0.05). The pharmacist-led MTM was effective in solving 69.8% of DRPs, improving and controlling the clinical parameters evaluated |
| Disciplinas: | Medicina |
| Palabras clave: | Geriatría, Neurología, Farmacología, Ancianos, Enfermedad de Alzheimer, Adherencia al tratamiento, Errores de medicación, Intervención farmacológica |
| Keyword: | Geriatrics, Neurology, Pharmacology, Aged, Alzheimer disease, Treatment adherence, Medication errors, Pharmacological intervention |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
