| Revista: | Brazilian Journal of Pharmaceutical Sciences |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000451798 |
| ISSN: | 1984-8250 |
| Autores: | Liaqat, Aroosa1 Mallhi, Tauqeer Hussain2 Khan, Yusra Habib2 Khokhar, Aisha3 Chaman, Sadia4 Ali, Muhammad1 |
| Instituciones: | 1University of the Punjab, University College of Pharmacy, Lahore, Punjab. Pakistán 2Jouf University, College of Pharmacy, Sakakah, Al-Jouf Province. Arabia Saudita 3Lahore College for Women University, Institute of Pharmacy, Lahore, Punjab. Pakistán 4University of Veterinary and Animal Sciences, Institute of Pharmaceutical Sciences, Lahore, Punjab. Pakistán |
| Año: | 2022 |
| Volumen: | 58 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Snakebite is one of the major health issues posing considerable morbidity and mortality. According to an estimate of World Health Organization (WHO) (World health organization, 2021) approximately 5 million people are bitten by several species of snakes resulting in up to 2.5 million envenomation cases annually. The mainstay of treatment for envenomation is intravenous administration of anti-snake venom. Although antivenom neutralizes the systemic effects but it does not relieve the symptoms such as venom-induced hemorrhage, necrosis and nephrotoxicity. Moreover, the use of antivenoms is associated with hypersensitivity reactions including urticaria, anaphylaxis, or serum sickness due to their heterologous property. Furthermore, stringent storage conditions and narrow specificity of antivenoms limit their use in both developed as well as developing countries. In this context, researchers have been searching for natural products and plant extracts to explore their antivenom activity along with anti-myotoxic, anti-hemorrhagic and anti-inflammatory properties. Plant remedies may prove to be an effective alternate for antivenom sera with less adverse events and better tolerability. To the best of our knowledge, this is the first comprehensive review of medicinal plants possessing anti-snake venom activities against certain species of snakes. The current review highlights the investigated plants with their phytochemical analysis to integrate the available information for future research and development of antivenom sera |
| Disciplinas: | Medicina |
| Palabras clave: | Toxicología, Mordeduras de serpiente, Veneno de víbora, Antivenenos, Plantas medicinales |
| Keyword: | Toxicology, Snake bites, Snake venom, Antivenoms, Medicinal plants |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
