A comparative study on biological activities of different solvent extracts from whole seed, seed coat and cotyledon of two Lathyrus species



Título del documento: A comparative study on biological activities of different solvent extracts from whole seed, seed coat and cotyledon of two Lathyrus species
Revista: Brazilian Journal of Pharmaceutical Sciences
Base de datos: PERIÓDICA
Número de sistema: 000451719
ISSN: 1984-8250
Autores: 1
2
3
4
Instituciones: 1Burdur Mehmet Akif Ersoy University, Faculty of Education, Istiklal Yerleskesi, Burdur. Turquía
2Burdur Mehmet Akif Ersoy University, Faculty of Health Sciences, Istiklal Yerleskesi, Burdur. Turquía
3Suleyman Demirel University Art and Science, Faculty Department of Chemistry, Isparta. Turquía
4Burdur Mehmet Akif Ersoy University, Vocational School of Higher Education, Istiklal Yerleskesi, Burdur. Turquía
Año:
Volumen: 58
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés The present study was conducted to assess the phenolic content, and antibacterial and antioxidant activities of Lathyrus L. species. The extraction of phenolic compounds from whole seeds, seed coat and cotyledon of Lathyrus hierosolymitanus Boiss. and Lathyrus annuus L. seeds was performed employing different solvents. Total phenolic content (TPC) was measured by Folin- Ciocalteau assay, while the antioxidant activity was determined by DPPH radical scavenging activity, and reducing power assay. It was found that TPC of extracts ranged from 0.12 mg to 6.53 mg GAE/gdw. For each solvent, seed coat extracts were generally observed to render higher TPC and antioxidant activities. There was a correlation between TPC and antioxidant activity. In addition, all extracts were also examined for their antimicrobial activity against Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa. Methanol extracts showed the highest antibacterial activity which is consistent with TPC, but there was no correlation between TPC and antibacterial activity. Solvents were observed to have effects on gallic acid, caffeic acid, and epicatechin extractions. HPLC analysis results of extracts confirmed methanol and ethanol as preferred solvents for phenolic extraction from Lathyrus sp. Phenolic content in the extracts could be suggested to contribute to their antioxidant and antibacterial activity
Disciplinas: Biología,
Química
Palabras clave: Fitoquímica,
Angiospermas,
Compuestos fenólicos,
Actividad antioxidante,
Actividad antibacteriana,
Lathyrus hierosolymitanus,
Lathyrus annuus,
Fabaceae
Keyword: Phytochemistry,
Angiosperms,
Phenolic compounds,
Antioxidant activity,
Antibacterial activity,
Lathyrus hierosolymitanus,
Lathyrus annuus,
Fabaceae
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