| Revista: | Brazilian journal of chemical engineering |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000308714 |
| ISSN: | 0104-6632 |
| Autores: | Gouveia, E.R1 Baptista-Neto, A Hokka, C.O Badino-Junior, A.C |
| Instituciones: | 1Universidade Federal de Sao Carlos, Departamento de Engenharia Quimica, Sao Carlos, Sao Paulo. Brasil |
| Año: | 2000 |
| Periodo: | Dic |
| Volumen: | 17 |
| Número: | 4-7 |
| Paginación: | 827-834 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | In the present work rheological characteristics and volumetric oxygen transfer coefficient (kLa) were investigated during batch cultivations of Streptomyces clavuligerus NRRL 3585 for production of clavulanic acid. The experimental rheological data could be adequately described in terms of the power law model and logistic equation. Significant changes in the rheological parameters consistency index (K) and flow behavior index (n) were observed with the fermentation evolution. Interesting correlations between the consistency index (K)/biomass concentration (C X) and the flow behavior index (n)/biomass concentration were proposed. Volumetric oxygen mass transfer coefficient (kLa) was determined by the gas balance method. Classical correlation relating the volumetric oxygen mass transfer coefficient to the operating conditions, physical and to transport properties, including apparent viscosity (muap), could be applied to the experimental results |
| Disciplinas: | Química |
| Palabras clave: | Química farmacéutica, Reología, Transferencia de oxígeno, Acido clavulánico, Streptomyces clavuligerus |
| Keyword: | Chemistry, Medicinal chemistry, Rheology, Oxygen transfer, Clavulanic acid, Streptomyces clavuligerus |
| Texto completo: | Texto completo (Ver HTML) |
