Selectivity in the extraction of 2-quinolone alkaloids with supercritical CO2



Título del documento: Selectivity in the extraction of 2-quinolone alkaloids with supercritical CO2
Revista: Brazilian journal of chemical engineering
Base de datos: PERIÓDICA
Número de sistema: 000309075
ISSN: 0104-6632
Autores: 1
2





Instituciones: 1Universidade Federal da Bahia, Faculdade de Farmacia, Salvador, Bahia. Brasil
2Universidade Federal da Bahia, Instituto de Quimica, Salvador, Bahia. Brasil
Año:
Periodo: Dic
Volumen: 23
Número: 4
Paginación: 525-530
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés This work describes the conditions for selective extraction of the alkaloids in Andreadoxa flava (Kallunki). The experiments were performed in a pilot plant SFE 500, in the following conditions. Extractor pressures 206.8 x 10(5), 241.3 x 10(5), 275.8 x 10(5) and 310.3 x 10(5) Pascal and pressures of 137.9 x 10(5), 69.0 x 10(5) and 55.2 x 10(5) Pascal for separators 6, 7 and 8 respectively. The temperatures were 40 °C in the extractor and 20 ºC in the separators. The samples, extracted from A. flava leaves, were analysed by ¹H NMR and GC/FID as well as by comparison with standards. This procedure allowed the identification for the first time of the 2-quinolone alkaloid 8-methoxy-N-methyl-flindersine in A. flava leaves of the. In addition, zanthophylline, 5-methoxyalmene and 8-methoxyflindersine were identified as the main alkaloids in leaves. Under the best conditions for zanthophylline extraction it was possible to obtain a purity of 79.4% while with other phytochemical technique 55.5% was obtained
Disciplinas: Química
Palabras clave: Fitoquímica,
Alcaloides,
Extracción supercrítica,
Dióxido de carbono,
Quinolonas,
Andreadoxa flava
Keyword: Chemistry,
Phytochemistry,
Alkaloids,
Supercritical extraction,
Carbon dioxide,
Quinolones,
Andreadoxa flava
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