| Revista: | Brazilian journal of chemical engineering |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000309057 |
| ISSN: | 0104-6632 |
| Autores: | Carvalho, P.O1 Cass, Q.B2 Calafatti, S. A3 Contesini, F.J Bizaco, R |
| Instituciones: | 1Universidade Sao Francisco, Faculdade de Farmacia, Braganca Paulista, Sao Paulo. Brasil 2Universidade Federal de Sao Carlos, Departamento de Quimica, Sao Carlos, Sao Paulo. Brasil 3Universidade Sao Francisco, Unidade Integrada de Farmacologia e Gastroenterologia Clinica, Braganca Paulista, Sao Paulo. Brasil |
| Año: | 2006 |
| Periodo: | Sep |
| Volumen: | 23 |
| Número: | 3 |
| Paginación: | 291-300 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental |
| Resumen en inglés | Given the inherent dangers associated with racemic pharmaceuticals, exhaustive studies of techniques designed to separate enantiomers have been conducted. This paper reports a brief review of the different physical, chemical, and enzymatic methods used for the enantiomeric separation of rac-ibuprofen. The possible contribution of each technique to the preparation of enantiomerically pure drugs is reviewed in the context of competitive approaches that depend on the scale of application, with special emphasis on the recent progress achieved in this particular area |
| Disciplinas: | Química |
| Palabras clave: | Química farmacéutica, Fármacos, Enantiómeros, Separación, Ibuprofeno |
| Keyword: | Chemistry, Medicinal chemistry, Drugs, Enantiomers, Separation methods, Ibuprofen |
| Texto completo: | Texto completo (Ver HTML) |
