Marcadores de proliferação celular na avaliação do crescimento do tumor sólido e ascítico de Ehrlich



Título del documento: Marcadores de proliferação celular na avaliação do crescimento do tumor sólido e ascítico de Ehrlich
Revista: Arquivo brasileiro de medicina veterinaria e zootecnia
Base de datos: PERIÓDICA
Número de sistema: 000287404
ISSN: 0102-0935
Autores: 1

Instituciones: 1Universidade Federal de Minas Gerais, Instituto de Ciencias Biologicas, Belo Horizonte, Minas Gerais. Brasil
Año:
Periodo: Ago
Volumen: 58
Número: 4
Paginación: 658-661
País: Brasil
Idioma: Portugués
Tipo de documento: Nota breve o noticia
Enfoque: Experimental
Resumen en inglés Twenty BALB/c mice were inoculated with cell suspension of Ehrlich tumor. Ten mice were inoculated in the cushion plant (solid form) and the other 10 in the peritoneum (ascitic form). Animals were euthanized on different times (7 and 14 days). Cytological and histological slides, immunohistochemical (PCNA) analysis and NORs silver impregnation technique were performed. The results showed more proliferation on the 7th day in the ascitic form and on 14th day in the solid form, using both analyses (PCNA and AgNORs). The alterations observed in the Ehrlich tumor’s proliferation activity suggested that the growth curve is different between ascitic and solid forms. In the first one, the proliferation peak occurs on the seventh day and in the solid tumor the growth curve was more delayed, showing increased proliferative potential after seven days
Disciplinas: Medicina veterinaria y zootecnia,
Biología
Palabras clave: Medicina veterinaria,
Biología celular,
Mamíferos,
Proliferación celular,
Tumor de Ehrlich,
AgNOR,
PCNA,
Marcadores,
Animales de laboratorio,
Roedores
Keyword: Veterinary medicine and animal husbandry,
Biology,
Veterinary medicine,
Cell biology,
Mammals,
Cell proliferation,
Ehrlich tumor,
AgNOR,
PCNA,
Markers,
Laboratory animals,
Rodents
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