Rapid identification system of frontal dysfunction in subclinical hepatic encephalopathy



Título del documento: Rapid identification system of frontal dysfunction in subclinical hepatic encephalopathy
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000407480
ISSN: 1665-2681
Autores: 1
2
2
1
2
2
2
Instituciones: 1Universita di Trieste, Clinica di Neurologia, Trieste, Friuli Venezia Giuli. Italia
2Fundacion Italiana di Fegato, Centro Studi Fegato, Trieste, Friuli Venezia Giuli. Italia
Año:
Periodo: Jul-Ago
Volumen: 15
Número: 4
Paginación: 559-567
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Liver disease is associated with cognitive dysfunction also at early stages, and minimal hepatic encephalopathy, affecting 20-70% of patients, is frequently under-recognized. The main purpose of this work was to demonstrate that a substantial number of patients, enrolled due to an acute confusional state in absence of a diagnosis of liver disease, suffers of hepatic encephalopathy. Material and methods. Material and methods. Before a diagnosis of a well-compensated liver diseases was performed, 410 patients with an acute confusional state were enrolled in this study. Results. Results. Even Results. in the presence of minimal alterations of hepatic function, the psychometric tests applied demonstrated early signs of cerebral frontal alteration. The alteration was associated with the severity of liver disease, paralleling the progression of the patient to minimal hepatic failure or chronic liver disease. Conclusions. Conclusions. These psychometric tests are essential to detect early and subclinical frontal failure. Frontal dysfunction may be a useful tool in the follow-up of these patients
Disciplinas: Medicina
Palabras clave: Diagnóstico,
Gastroenterología,
Neurología,
Enfermedad hepática,
Disfunción cognitiva,
Encefalopatía hepática,
Apatía,
Pruebas psicométricas
Keyword: Medicine,
Diagnosis,
Gastroenterology,
Neurology,
Liver diseases,
Cognitive dysfunction,
Hepatic encephalopathy,
Apathy,
Psychometric tests
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