| Revista: | Anais da Academia Brasileira de Ciencias |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000420604 |
| ISSN: | 0001-3765 |
| Autores: | Queiroz, Estela R1 Abreu, Celeste M.P. de1 Rocha, Denise A1 Sousa, Raimundo V. de2 Fraguas, Rodrigo M1 Braga, Mariana A1 Cesar, Pedro H.S1 |
| Instituciones: | 1Universidade Federal de Lavras, Departamento de Quimica, Lavras, Minas Gerais. Brasil 2Universidade Federal de Lavras, Departamento de Medicina Veterinaria, Lavras, Minas Gerais. Brasil |
| Año: | 2018 |
| Periodo: | Mar |
| Volumen: | 90 |
| Número: | 1 |
| Paginación: | 267-282 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Dyslipidemias are associated with the incidence of cardiovascular diseases, obesity, diabetes, hypertension and hepatic steatosis, being the cause of morbidity and mortality. This study investigated the effects of lychee peel flour (PF) on serum levels of total cholesterol (TC), low-density lipoprotein (LDL-c), triacylglycerols (TAG) and various parameters related to obesity, in rats fed a hypercholesterolemic diet. Therefore, 20 male rats were used. In the first 21 days, the animals were fed a hypercholesterolemic diet, except for control group. In the following 21 days, their diets were modified, and they received a standard diet (Control); hypercholesterolemic (Hyper); hypercholesterolemic + 5% PF (PF5) and hypercholesterolemic + 10% PF (PF10). The results revealed that PF intake attenuated weight gain, reduced body mass index, glucose and the levels of TAG, TC, LDL-c, hepatic enzymes and leptin, besides the percentage of hepatic lipids, liver lipid peroxidation and frequency of severe steatosis. Histological studies of the aorta did not show the formation of the atheromatous plaque. These results reinforce its potential to reduce the risk of diseases associated with obesity |
| Disciplinas: | Agrociencias, Medicina |
| Palabras clave: | Metabolismo y nutrición, Farmacología, Frutales, Cáscara, Hepatoprotección, Colesterol, Peroxidación lipídica, Esteatosis, Litchi chinensis |
| Keyword: | Metabolism and nutrition, Pharmacology, Fruit trees, Peel, Hepatoprotection, Cholesterol, Lipid peroxidation, Steatosis, Litchi chinensis |
| Texto completo: | Texto completo (Ver HTML) |
