| Revista: | Acta scientiarum. Biological sciences |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000433546 |
| ISSN: | 1679-9283 |
| Autores: | Grigoletto, Diana Fortkamp1 Correia, Ana Maria Lima2 Abraham, Wolf-Rainer3 Rodrigues, Andre2 Assis, Marco Antonio2 Ferreira, Antonio Gilberto4 Massaroli, Michelli4 Lira, Simone Possedente de1 |
| Instituciones: | 1Universidade de Sao Paulo, Escola Superior de Agricultura "Luiz de Queiroz", Piracicaba, Sao Paulo. Brasil 2Universidade Estadual Paulista "Julio de Mesquita Filho", Rio Claro, Sao Paulo. Brasil 3Helmholtz Centre for Infection Research, Chemical Microbiology, Braunschweig, Niedersachsen. Alemania 4Universidade Federal de Sao Carlos, Sao Carlos, Sao Paulo. Brasil |
| Año: | 2019 |
| Volumen: | 41 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Fungi are present in the most diverse environments including the interior of plant tissues, living as endophytes without causing apparent damage. These endophytes are producers of secondary metabolites, also known as natural products, such as fungicides. Here, we evaluated the ethyl acetate fractions obtained from endophytic fungiisolated from plants in the genus Begonia. The fractions were submitted to inhibitorytest against the plant pathogens Diaporthe phaseolorum and Colletotrichum gloeosporioides. From the 88 ethyl acetate fractions evaluated, 14.7 % inhibited C. gloeosporioidesand 11.3 %inhibited D. phaseolorum. One fungal isolate displaying an active fraction was selected for chemical investigation. The fungus identified as Neopestalotiopsissp., produced a compound that was active against D. phaseolorum, with a MIC of 312 μg mL-1(1,695.3 μM). The compound was identified by mass spectrometry and 1H NMR as the known compound fumiquinone B. The results highlight that the endophytes are capable of producing compounds that may be used to control plant pathogens. The compound fumiquinone B is reported for the first time as an antifungal agent against D. phaseolorum, a relevant plant pathogen worldwide. This is also the first report of the production of fumiquinone B by the genus Neopestalotiopsis |
| Disciplinas: | Biología, Química |
| Palabras clave: | Hongos, Fitoquímica, Hongos endofíticos, Metabolitos secundarios, Actividad antifúngica, Fumiquinona B, Neopestalotiopsis |
| Keyword: | Fungi, Phytochemistry, Endophytic fungi, Secondary metabolites, Antifungal activity, Fumiquinone B, Neopestalotiopsis |
| Texto completo: | http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/48785/751375149130 |
