| Revista: | Acta scientiarum. Biological sciences |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000433512 |
| ISSN: | 1679-9283 |
| Autores: | Rocha, Denise Alvarenga1 Queiroz, Estela de Rezende1 Botelho, Lucimara Nazaré Silva1 Fráguas, Rodrigo Martins1 Santos, Cláudia Mendes dos1 Abreu, Celeste Maria Patto1 Sousa, Raimundo Vicente de2 |
| Instituciones: | 1Universidade Federal de Lavras, Departamento de Quimica, Lavras, Minas Gerais. Brasil 2Universidade Federal de Lavras, Departamento de Medicina Veterinaria, Lavras, Minas Gerais. Brasil |
| Año: | 2019 |
| Volumen: | 41 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | The pineapple is a fruit that has wide acceptance worldwide both in natural form, as industrialized. Your peel is a residue generated by food industries and from this residue can obtain a protein extract which is a good source of bromelain. This study aimed to obtain a protein extract from pineapple peel, evaluate its enzyme activity and its healing properties in skin lesions in rats. Seven animal groups were used: control, treated with 5% of protein extract, 10% of protein extract and pure protein extract; 5% of commercial bromelain, 10% of commercial bromelain and pure commercial bromelain. The animals were subjected to a tissue incision and treated for 21 days. Proteolytic and specific activities of the protein extract were 1.30 U mg-1 and 45 x 10-3 U μg-1 and, for commercial bromelain, 1.04 U mg-1 and 6 x 10-3 U μg-1, respectively. In the histology of the lesion, there was no significant difference between the control and treated groups; however, macroscopically, the prepared topical formulations assisted in the recovery of skin lesions, providing a significant reduction in their width, in the groups treated with pure protein extract, 5 and 10% commercial bromelain, and pure bromelain |
| Disciplinas: | Biología, Medicina |
| Palabras clave: | Química farmacéutica, Dermatología, Lesiones de la piel, Cicatrización, Bromelaína, Actividad enzimática, Cáscara de piña |
| Keyword: | Medicinal chemistry, Dermatology, Skin lesions, Healing, Bromelain, Enzymatic activity, Pineapple peel |
| Texto completo: | http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/41466/pdf |
