Estudo morfológico das entero-anastomoses com suturas em pontos separados complementados com adesivo sintético ou biológico em coelho



Título del documento: Estudo morfológico das entero-anastomoses com suturas em pontos separados complementados com adesivo sintético ou biológico em coelho
Revista: Acta cirurgica brasileira
Base de datos: PERIÓDICA
Número de sistema: 000286360
ISSN: 0102-8650
Autores: 1
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Instituciones: 1Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Sao Paulo. Brasil
Año:
Periodo: Jul-Ago
Volumen: 19
Número: 4
Paginación: 393-405
País: Brasil
Idioma: Portugués
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en inglés PURPOSE: The aim of the research was to verify the efficacy of the fibrin or cianoacrylate glue as coadjuvant in the intestinals anastomosis of rabbits. METHODS: Eighty rabbits, lineage New Zealand, males, adults, were submitted to enterectomy of 3cm and enteroraphy distributed in four groups: Group A (two equidistants stitches); Group B (four equidistants stitches); Group C (six equidistants stitches); Group D (eight equidistants stitches). In 14 days of observation, the animals were submitted to median laparotomy for macroscopic study of the abdominal cavity for identification and evaluation of adherence, dehiscence and fistula. The segment anastomosed was removed and was maked mould of alginate for later evaluation of the index of stenosis. The parts removed were processed for histological study and evaluation of collagen, macrofages, vessels and granulomas. RESULTS: Significant difference was not presented in the evaluation of dehiscence and fistula with the two adhesives between the four subgroups. The adherence occurred in higher number in the subgroups of the synthetical adhesive. The index of stenosis was higher in the animals of the synthetical adhesive only in the subgroups with two and eight stitches. The histological analysis showed that in all the parameters evaluated (macrofages, vessels and granulomas) did not present significant difference between the two kinds of adhesives. In relation the percentagem of collagen was verified that presented significant difference in group B in that the synthetical adhesive was smaller that the biological adhesive. CONCLUSION: The biological adhesive of fibrin show more efficacy that the synthetical adhesive as coadjunvants of suture in the intestinals anastomosis
Resumen en portugués que o biológico. CONCLUSÃO: O adesivo biológico de fibrina mostra mais eficácia que o adesivo sintético como complemento de suturas nas anastomoses intestinais
Disciplinas: Medicina
Palabras clave: Cirugía,
Medicina experimental,
Anastomosis,
Intestinos,
Cianoacrilato,
Fibrina,
Adhesivos
Keyword: Medicine,
Experimental medicine,
Surgery,
Intestines,
Anastomosis,
Cyanoacrylate,
Fibrin,
Adhesives
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