Study of the relationship between Androctonus crassicauda (Oliver, 1807; Scorpiones, Buthidae) venom toxicity and telson size, weight and storing condition



Título del documento: Study of the relationship between Androctonus crassicauda (Oliver, 1807; Scorpiones, Buthidae) venom toxicity and telson size, weight and storing condition
Revista: The journal of venomous animals and toxins including tropical diseases
Base de datos: PERIÓDICA
Número de sistema: 000298973
ISSN: 1678-9199
Autores: 1


2
Instituciones: 1Refik Saydam Hygiene Center, Ankara. Turquía
2Ankara University, Faculty of Veterinary Medicine, Ankara. Turquía
Año:
Periodo: Abr
Volumen: 12
Número: 2
Paginación: 297-309
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Scorpions are included in the order Scorpiones; class Arachnida. Lethal scorpions are mostly of the Buthidae family. Among these, species belonging to Androctonus, Leiurus and Mesobuthus genera cause most scorpion envenomations in Turkey. This study was performed aiming the production of antivenom by using Androctonus crassicauda telsons. Venom toxicity is related to telson weight, size, and storing condition (open or closed). Telsons of A. crassicauda were collected in Southeastern Anatolia (especially in Harran town, Sanliurfa), Turkey. They were separated according to weight, size, and storing condition - open (a) and closed (b). Venom solution was prepared by maceration of telsons. Swiss albino mice were used to determine the lethal dose 50% (LD50), which was as follows: Group 1a - 2.31mg; Group 1b - 2.66mg; Group 2a - 2.32mg; Group 2b - 2.66mg; Group 3a - 6.66mg; Group 3b - 6.88mg. Among the groups of telsons, the first and the second groups showed different characteristics. However, there were no differences between their toxicity. In the third group, a fourfold amount of telsons was used for toxicity. In other words, telsons weighting from 19.99 to 20mg (first group) and from 29.99 to 30mg (second group) presented similar LD50 values, and telsons weighting from 10 to 19.99mg (third group) showed a fourfold higher LD50 value. This difference was caused by the maturity of scorpions and venom toxicity was related to their size. The first and second groups were considered to be mature and the third group, not adult. Therefore, w
Disciplinas: Biología
Palabras clave: Anatomía e histología,
Quelicerados,
Escorpiones,
Telson,
Morfología,
Crecimiento,
Toxicidad aguda,
Androctonus crassicauda,
Buthidae
Keyword: Biology,
Anatomy and histology,
Chelicerata,
Scorpions,
Telson,
Morphology,
Growth,
Acute toxicity,
Androctonus crassicauda,
Buthidae
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