Intraspecific variation in protein pattern of red scorpion (Mesobuthus tamulus, coconsis, pocock) venoms from Western and Southern India
Título del documento: Intraspecific variation in protein pattern of red scorpion (Mesobuthus tamulus, coconsis, pocock) venoms from Western and Southern India
Revista: The journal of venomous animals and toxins including tropical diseases
Base de datos: PERIÓDICA
Número de sistema: 000298938
ISSN: 1678-9199
Autores: 1



2
Instituciones: 1Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Department of Pharmaceutical Chemistry, Pune, Maharashtra. India
2Haffkine Biopharmaceutical Corporation Ltd., Pune, Maharashtra. India
Año:
Volumen: 12
Número: 4
Paginación: 612-619
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Red scorpions Mesobuthus tamulus (Coconsis, Pocock) were obtained from different regions of West and South India (Ratnagiri, Chiplun and Ahmednagar from Maharashtra and Chennai from Tamil Nadu, respectively). Their venoms composition was analyzed using gel electrophoresis (SDS-PAGE). All venom samples shared six bands of 170, 80, 60, 57, 43, and 38 kDa molecular weights. Bands of 115 kDa and 51.5 kDa were characteristic of venoms obtained from red scorpions of Chiplun region, and the 26kDa band was absent in scorpion venom from Tamil Nadu. The separated protein band patterns suggest that the venoms from Ratnagiri, Ahmednagar and Tamil Nadu had high similarities in their biochemical composition but differed from that of Chiplun region. These data were also supported by the Jaccard (J) index. The J value was 0.33 for venom obtained from Ratnagiri-Ahmednagar, 0.31 for venom from Ratnagiri-Tamil Nadu, and 0.3 for venom from Ratnagiri-Chiplun region. This suggests the existence of genetic variation among the different strains of red scorpion in western and southern India. The antiserum produced by Haffkine Biopharmaceuticals Corporation Ltd. completely neutralized proteins of venoms from all the regions studied
Disciplinas: Biología
Palabras clave: Quelicerados,
Bioquímica,
Veneno de escorpión,
Perfil proteico,
Variación intraespecífica,
Mesobuthus tamulus,
Buthidae
Keyword: Biology,
Chelicerata,
Biochemistry,
Scorpion venom,
Protein profile,
Intraspecific variation,
Mesobuthus tamulus,
Buthidae
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