Vancomycin-resistant enterococci, colonizing the intestinal tract of patients in a university hospital in greece



Título del documento: Vancomycin-resistant enterococci, colonizing the intestinal tract of patients in a university hospital in greece
Revista: The brazilian journal of infectious diseases
Base de datos: PERIÓDICA
Número de sistema: 000291043
ISSN: 1413-8670
Autores: 1
2
3



4

Instituciones: 1AHEPA University Hospital, First Internal Medicine Department, Thessaloniki. Grecia
2AHEPA University Hospital, Microbiology Department, Thessaloniki. Grecia
3AHEPA University Hospital, Infectious Diseases Division, Thessaloniki. Grecia
4University of Heraklion, Heraklion, Crete. Grecia
Año:
Periodo: Jun
Volumen: 10
Número: 3
Paginación: 179-184
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en inglés OBJECTIVE: Determine the prevalence of Vancomycin-resistant enterococci (VRE) colonizing the intestinal tract of hospitalized patients and define risk factors. MATERIAL AND METHODS: A point prevalence survey of VRE fecal carriage was carried out among patients who stayed at a 600-bed teaching hospital for at least two days. Resistance to vancomycin was detected by the E-test method. Epidemiological data was recorded for all patients included in the study and was used for the risk factor analysis. RESULTS: A total of 128 patients hospitalized for at least two days were enrolled in this investigation. Thirty-nine patients (30.5%) were colonized with vancomycin-resistant enterococci. Twenty-three of the 39 strains were identified as Enterococcus faecium, 13 were identified as Enterococcus gallinarum and three strains as Enterococcus casseliflavus. The risk factors that were significantly associated with VRE colonization included length of hospital stay (13.2 days vs. 8.6 days), age (60.7 years vs. 47.7 years) and the presence of underlying malignancies (28.2% vs. 11.2%). An association was found between VRE colonization and the use of antimicrobials with anaerobic activity, such as metronidazole, piperacillin/tazobactam and imipenem. The use of vancomycin was associated with VRE colonization in the intensive care unit. CONCLUSIONS: VRE colonization must be monitored, and risk factors should be determined, because they are useful for screening hospitalized patients for VRE colonization in order to establish prevention and control measu
Disciplinas: Medicina,
Biología
Palabras clave: Farmacología,
Hospitales,
Microbiología,
Bacterias,
Vancomicina,
Resistencia,
Enterococos,
Tracto intestinal,
Pacientes hospitalizados
Keyword: Medicine,
Biology,
Hospitals,
Microbiology,
Pharmacology,
Bacteria,
Vancomycin,
Resistance,
Enterococci,
Intestinal tract,
Hospitalized patients
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