Revista: | The brazilian journal of infectious diseases |
Base de datos: | PERIÓDICA |
Número de sistema: | 000290667 |
ISSN: | 1413-8670 |
Autores: | Oplustil, Carmen Paz1 Nunes, Rogerio2 Mendes, Caio3 |
Instituciones: | 1Universidade de Sao Paulo, Hospital da Faculdade de Medicina, Sao Paulo. Brasil 2Pfizer Laboratories, Sao Paulo. Brasil 3Universidade de Sao Paulo, Divisao de Doencas Infecciosas e Parasitarias, Sao Paulo. Brasil |
Año: | 2001 |
Periodo: | Feb |
Volumen: | 5 |
Número: | 1 |
Paginación: | 8-12 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Caso clínico, analítico |
Resumen en inglés | Surveillance programs are essential to detect the increase of antimicrobial resistance, and several different programs are being conducted in many countries. The RESISTNET is a surveillance program for bacterial resistance against several antimicrobial agents initiated in 1998 among Latin American countries. In Brazil, several centers were invited to join this surveillance and a total of 11 centers (6 from São Paulo and 5 from other states) participated in the study. All results were analyzed using the WHONET program. A total of 894 Escherichia coli, 386 Klebsiella pneumoniae, 70 Shigella spp and 57 Salmonella spp strains were analyzed in this study from April, 1998, to April, 1999. Susceptibility testing was performed by the disk diffusion method using NCCLS 1998 guidelines for several different drugs. For all strains, imipenem was the most effective drug (100% of the strains were susceptible). Klebsiella pneumoniae presented a high resistance rate to ampicillin (96.4%). The rate of probable ESBL producers among K. pneumoniae strains was 36.3%, most of them being isolated from catheters (58.8%). Among all Escherichia coli strains analyzed, the highest resistance rate was found for trimethoprim/sulfamethoxazole (46.9%) and the majority of the resistant strains were isolated from urine samples (47.8%). Among Salmonella spp, the resistance rates were low for all antibiotics tested. For Shigella spp strains there was a high resistance to trimethoprim/sulfamethoxazole (80.0%). No resistance to ceftriaxone was observed in these strains |
Disciplinas: | Medicina |
Palabras clave: | Farmacología, Microbiología, Salud pública, Bacterias, Resistencia antimicrobiana, Antibióticos, Vigilancia, Klebsiella pneumoniae |
Keyword: | Medicine, Microbiology, Pharmacology, Public health, Bacteria, Antimicrobial resistance, Antibiotics, Surveillance, Klebsiella pneumoniae |
Texto completo: | Texto completo (Ver HTML) |