Human Papillomavirus prevalence, viral load and cervical intraepithelial neoplasia in HIV-infected women



Título del documento: Human Papillomavirus prevalence, viral load and cervical intraepithelial neoplasia in HIV-infected women
Revista: The brazilian journal of infectious diseases
Base de datos: PERIÓDICA
Número de sistema: 000290696
ISSN: 1413-8670
Autores: 1









Instituciones: 1Instituto de Medicina Tropical, Laboratorio de Virologia, Sao Paulo. Brasil
Año:
Periodo: Jun
Volumen: 6
Número: 3
Paginación: 129-134
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico
Resumen en inglés ABSTRACT HIV-infected women from São Paulo city were enrolled in a cross-sectional study on Human Papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) prevalence and their association with laboratory markers of AIDS, namely HIV viral load and CD4+ cell counts. A cervical specimen was collected and submitted to Hybrid Capture, a test for HPV viral load determination. HPV-DNA was detected in 173 of 265 women (64.5%). Twenty (7.5%) women were infected by one or more low-risk viruses, 89 (33%) by one or more high-risk viruses, and 64 (24%) harbored at least one HPV type from each risk group. Abnormal smears were observed in 19% of the patients, though there were no invasive carcinomas. Severely immunosuppressed patients (CD4/µL <100) were at the greatest risk of having a cytological abnormality and a high high-risk HPV viral load
Disciplinas: Medicina
Palabras clave: Oncología,
Inmunología,
Virus,
Papilomavirus,
Neoplasia intraepitelial cervical,
VIH,
SIDA
Keyword: Medicine,
Oncology,
Immunology,
Virus,
Human papillomavirus,
Cervical intraepithelial neoplasm,
HIV,
AIDS
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