| Revista: | The brazilian journal of infectious diseases |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000291035 |
| ISSN: | 1413-8670 |
| Autores: | Barberino, Maria Goreth1 Silva, Nanci2 Rebouças, Carla3 Barreiro, Katarine Alcantara, Ana Paula4 Netto, Eduardo M Albuquerque, Ligia Brites, Carlos |
| Instituciones: | 1Hospital Alianca, Salvador, Bahia. Brasil 2Hospital Espanhol, Salvador, Bahia. Brasil 3Universidade Federal da Bahia, Salvador, Bahia. Brasil 4Hospital Santo Amaro, Salvador, Bahia. Brasil |
| Año: | 2006 |
| Periodo: | Feb |
| Volumen: | 10 |
| Número: | 1 |
| Paginación: | 36-40 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico |
| Resumen en inglés | Invasive infections caused by Candida spp. are an important problem in immunocompromised patients. There is scarce data on the epidemiology of blood stream candidiasis in Salvador, Brazil. This study evaluates the risk factors associated with candidemia, among patients admitted to three tertiary, private hospitals, in Salvador, Brazil. We conducted a case-control, retrospective study to compare patients with diagnosis of candidemia in three different tertiary hospitals in Salvador, Brazil. Patients were matched for nosocomial, acquired infections, according to the causal agent: cases were defined by positive blood cultures for Candida species. Controls were those patients who had a diagnosis of systemic bacterial infection, with a positive blood culture to any bacteria, within the same time period (± 30 days) of case identification. The groups were compared for the main known risk factors for candidemia and for mortality rates. A hundred thirty-eight patients were identified. Among the 69 cases, only 14 were diagnosed as infected by Candida albicans. Candida species were defined in only eight cultures: C. tropicalis (4 cases), C. glabrata, C. parapsilosis, C. guillermondi, C. formata (1 case each). The main risk factors, identified in a univariate analysis, were: presence of a central venous catheter (CVC), use of parenteral nutrition support (PNS), previous exposure to antibiotics, and chronic renal failure (CRF). No association was detected with surgical procedures, diabetes mellitus, neutropenia or malignancies. Patients were more likely to die during the hospitalization period, but the rates of death caused by the infections were similar for cases and controls. The length of hospitalization was similar for both groups, as well as the time for a positive blood culture. Blood stream infection by Candida spp. is associated with CVC, PNS, previous use of antibiotics, and CRF. The higher mortality rate for cases probably better reflects the severity of .. |
| Disciplinas: | Medicina, Biología |
| Palabras clave: | Diagnóstico, Bacterias, Hongos, Candidiasis invasiva, Factores de riesgo, Bacteremia |
| Keyword: | Medicine, Biology, Diagnosis, Bacteria, Fungi, Invasive candidiasis, Risk factors, Bacteremia |
| Texto completo: | Texto completo (Ver HTML) |
