| Revista: | The brazilian journal of infectious diseases |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000290909 |
| ISSN: | 1413-8670 |
| Autores: | Klautau, Giselle Burlamaqui1 Kuschnaroff, Tuba M |
| Instituciones: | 1Instituto Emilio Ribas, Sao Paulo. Brasil |
| Año: | 2005 |
| Periodo: | Dic |
| Volumen: | 9 |
| Número: | 6 |
| Paginación: | 464-478 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico |
| Resumen en inglés | Tuberculosis (TB)/HIV co-infection significantly changes the natural history of both diseases. Proper comprehension and clinical management of co-infected TB/HIV patients is still a challenge, particularly in places like Brazil, where both types of infection are prevalent. Evaluate the frequency of the clinical forms of TB in HIV-infected patients; correlate the clinical forms of TB with the level of immunodeficiency; evaluate the response to therapy with different regimens for the treatment of TB; identify potential prognostic factors in TB/HIV patients.The following data were collected at the beginning of the study: medical history, epidemiological background, physical examination, and laboratory evaluation (complete blood cell count, T lymphocyte subsets, viral load and tuberculin test). Monthly clinical follow-up was performed, with attention to adverse reactions to tuberculostatic drugs. TCD4+/CD8+ lymphocyte counts and quantification of the viral load were performed after 2, 4, 6, 10 and 15 months of follow-up. The study population consisted of 78 patients (45 males and 33 females) and their mean age was 36.4 ± 7.9 years The mean TCD4+ count values were higher in patients with the cavitary pulmonary form and lower in patients with disseminated forms. There were no significant differences in the mean TCD8+ cells counts . in the different clinical forms of TB. However, the mean laboratory values for hemoglobin, hematocrit and leucocytes at study entry did differ significantly ... |
| Disciplinas: | Medicina |
| Palabras clave: | Diagnóstico, Microbiología, Inmunología, Tuberculosis, Factores pronósticos, Co-infection TB/VIH, HAART |
| Keyword: | Medicine, Diagnosis, Microbiology, Tuberculosis, Prognostic factors, Co-infection TB/HIV, HAART, Immunology |
| Texto completo: | Texto completo (Ver HTML) |
