| Revista: | The brazilian journal of infectious diseases |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000291046 |
| ISSN: | 1413-8670 |
| Autores: | https://biblat.unam.mx/es/frecuencias/autor1 Parana, Raymundo Cavalcante, Daniel |
| Instituciones: | 1Schinoni, María Isabel, Hospital Universitario Edgard Santos, Salvador, Bahia. Brasil |
| Año: | 2006 |
| Periodo: | Abr |
| Volumen: | 10 |
| Número: | 3 |
| Paginación: | 117-121 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental |
| Resumen en inglés | Hepatitis C is a worldwide endemic disease, affecting roughly 200 million people. It has a variable prognosis, depending on the progression to fibrosis. During the last five years, the importance of apoptosis for the pathogenesis of various diseases, including hepatitis, has been recognized. It has been suggested that an increase in T cell-apoptosis during a hepatitis C virus infection is the cause of impaired regulation of the immune cellular response, helping to maintain infection. Thus, the interest in discovering the probable mechanisms by which the hepatitis C virus perpetuates in the liver, and to determine the conditions that predispose for progression of this disease, makes investigation of apoptosis in hepatic injury of great interest. We have made an overview of the various mechanisms by which the cell, more specifically the hepatic cell, is affected by apoptosis, and how it interacts with the hepatitis C virus and the immune system |
| Disciplinas: | Biología, Medicina |
| Palabras clave: | Biología celular, Virus, Gastroenterología, Apoptosis, Hepatitis C, Fibrosis hepática |
| Keyword: | Biology, Medicine, Cell biology, Virus, Gastroenterology, Apoptosis, Hepatitis C, Liver fibrosis |
| Texto completo: | Texto completo (Ver HTML) |
