| Revista: | Revista médica de Chile |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000333966 |
| ISSN: | 0034-9887 |
| Autores: | Stockins, Benjamín1 Albornoz, Francisco2 Martínez, Darío3 Campos, Pabla4 Gajardo, Jorge5 Lamich, Rubén6 Manríquez, Leopoldo7 Pérez, Víctor8 Rojo, Pamela9 Sepúlveda, Pablo10 Pumarino, María Gabriela11 Corbalán, Ramón12 |
| Instituciones: | 1Universidad de La Frontera, Hospital Dr. Hernán Henríquez, Temuco, Cautín. Chile 2Hospital Las Higueras, Talcahuano, Concepción. Chile 3Hospital San Borja Arriarán, Santiago de Chile. Chile 4Hospital Posta Central, Santiago de Chile. Chile 5Sanatorio Alemán, Concepción. Chile 6Hospital Barros Luco-Trudeau, Santiago de Chile. Chile 7Hospital Regional de Rancagua, Rancagua, Cachapoal. Chile 8Hospital del Salvador, Santiago de Chile. Chile 9Clínica Dávila, Santiago de Chile. Chile 10Hospital San Juan de Dios, Santiago de Chile. Chile 11Sanofi-Aventis, Santiago de Chile. Chile 12Pontificia Universidad Católica de Chile, Santiago de Chile. Chile |
| Año: | 2011 |
| Periodo: | Ene |
| Volumen: | 139 |
| Número: | 1 |
| Paginación: | 19-26 |
| País: | Chile |
| Idioma: | Español |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico, analítico |
| Resumen en inglés | Background: Guidelines for the management of unstable angina (UA) and non ST elevation myocardial infarction (NSTEMI) have been issued, however cu- rrent practices are unknown in Chile. Aim: To evaluate in a prospective cohort of NSTEMI patients the current practices, treatments and risk factors. Material and Methods: One year prospective International non interventional registry, conducted in Chile between January 2005 and November 2006. Results: Two hundred thirty three Chilean NSTEMI patients were enrolled. Mortality was 5.5% at the end of the follow-up. Mean age was 61.6 years, and 30.6% were female. Most of the patients had at least one risk factor (98%): hypertension (84%), previous myocardial infarc- tion (33%), dyslipidemia (54%), diabetes (33%), current smoking (30%). Main procedures during the hospitalization were coronary angiogram (67%), angioplasty (33%; 88% with stent) and coronary bypass surgery (7%). During procedures, 31% of patients received clopidogrel, and 4.2% glycoprotein IIb/IIIa antagonists. Medi- cal management was selected for 60% of patients. In comparison to men, women received less interventional procedures despite having more risk factors. Treatments prescribed at discharge were aspirin (97%), clopidogrel (49%), beta blockers (78%), diuretics (21%), lipid lowering agents (78%), oral hypoglycemic agents (13%) and insulin (9%). At the end of the 1-year follow-up, treatments were aspirin (84%), beta blockers (72%), diuretics (19%), and dual antiplatelet therapy with clopidogrel (16%). Conclusions: A high prevalence of multiple risk factors for cardiovascular disease in Chilean patients with NSTEMI was observed. More aggressive primary and secondary preventive measures are urgently needed. Use of therapies proposed in the guidelines is high, but dual antiplatelet therapy is less than 50% at discharge and decreases during the one year-follow-up |
| Disciplinas: | Medicina |
| Palabras clave: | Sistema cardiovascular, Terapéutica y rehabilitación, Enfermedad coronaria, Factores de riesgo, Infarto al miocardio |
| Keyword: | Medicine, Cardiovascular system, Therapeutics and rehabilitation, Coronary diseases, Risk factors, Myocardial infarction |
| Texto completo: | Texto completo (Ver PDF) |
