| Revista: | Revista médica de Chile |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000270834 |
| ISSN: | 0034-9887 |
| Autores: | Espinoza, Francisco1 Leal, José Luis Arenas, Guillermo2 |
| Instituciones: | 1Universidad de los Andes, Facultad de Medicina, Santiago de Chile. Chile 2Hospital Parroquial de San Bernardo, Servicio de Medicina Interna, Santiago de Chile. Chile |
| Año: | 2007 |
| Periodo: | Dic |
| Volumen: | 135 |
| Número: | 12 |
| Paginación: | 1572-1576 |
| País: | Chile |
| Idioma: | Español |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico |
| Resumen en inglés | Thrombotic thrombocytopenic purpura presents as a multisystemic disease with thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological and renal involvement. We report a 24 years-old male presenting with purpura and a generalized seizure. His blood tests showed an hemolytic anemia, unconjungated hyperbilirubinemia, increased lactated dehydrogenase, thrombocytopenia and impairment of renal function. He was initially treated with daily plasmapheresis and steroids without improvement. Due to persistence of the disease, he was treated with two doses of intravenous vincristine in four days, with clinical and laboratory improvement. He was discharged 40 days after the last dose of vincristine, in good conditions |
| Disciplinas: | Medicina |
| Palabras clave: | Hematología, Terapéutica y rehabilitación, Púrpura trombocitópenica trombótica, Anemia hemolítica, Plasmaféresis, Vincristina |
| Keyword: | Medicine, Hematology, Therapeutics and rehabilitation, Thrombotic thrombocytopenic purpura, Hemolytic anemia, Plasmapheresis, Vincristine |
| Texto completo: | Texto completo (Ver HTML) |
