| Revista: | Revista médica de Chile |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000448929 |
| ISSN: | 0034-9887 |
| Autores: | Kerkhof, Peter L.M1 Díaz Navarro, Rienzi2 Heyndrickx, Guy R3 Handly, Neal4 |
| Instituciones: | 1Amsterdam University Medical Centers, Department of Radiology and Nuclear Medicine, Amsterdam. Países Bajos 2Universidad de Valparaíso, Escuela de Medicina, Valparaíso. Chile 3Cardiovascular Center, Aalst, Oost Vlaanderen. Bélgica 4Drexel University, College of Medicine, Philadelphia, Pennsylvania. Estados Unidos de América |
| Año: | 2022 |
| Volumen: | 150 |
| Número: | 2 |
| Paginación: | 232-240 |
| País: | Chile |
| Idioma: | Español |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Ejection fraction (EF) is defined by the ratio of end-systolic volume (ESV) and end-diastolic volume (EDV). The resulting fraction is a dimensionless number whose interpretation is ambiguous and most likely misleading. Despite this limitation, EF is widely accepted as a clinical marker of cardiac function. In this article we analyze the role of ESV, a fundamental variable of ventricular mechanics, compared with the popular EF. Common physiology-based mathematics can explain a simple association between EF and ESV. This concept is illustrated by a detailed analysis of the information obtained from angiocardiography, echocardiography and cardiac magnetic resonance studies. EF versus ESV produces a non-linear curve. For a small ESV, the EF approaches 100%, while for a large ESV, the EF gradually decreases toward zero. This elemental relationship is commonly observed in innervated natural hearts. Thus, the popularity of EF mostly derives from a fortuitous connection with the pivotal variable ESV. Alongside this finding, we unfold historical events that facilitated the emergence of EF as a result of serendipity. Our physiology-based approach denounces the circumstantial theories invoked to justify the importance of EF as an index of cardiac function, which are critically discussed. EF appears to be nothing more than a blessing in disguise. For this reason, we propose the ESV as a more logical metric for the analysis of ventricular function |
| Disciplinas: | Medicina |
| Palabras clave: | Sistema cardiovascular, Corazón, Ventrículos, Falla cardiaca, Disfunción ventricular, Fraccion de eyección |
| Keyword: | Cardiovascular system, Heart, Ventricles, Heart failure, Ventricular dysfunction, Ejection fraction |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
