| Revista: | Revista latinoamericana de hipertensión |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000339143 |
| ISSN: | 1856-4550 |
| Autores: | Torrelas, Yulan1 Pérez Aguilar, Mary Carmen2 Ramos, Belkis1 Franco Useche, Antonio1 Ibarra, Alba2 Rodríguez Bonfante, Claudina2 Bonfante Cabarcas, Rafael2 |
| Instituciones: | 1Universidad Central de Venezuela, Hospital Antonio María Pineda, Barquisimeto, Lara. Venezuela 2Universidad Centroccidental "Lisandro Alvarado", Decanato de Ciencias de la Salud, Barquisimeto, Lara. Venezuela |
| Año: | 2010 |
| Volumen: | 5 |
| Número: | 2 |
| Paginación: | 38-42 |
| País: | Venezuela |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | With the aim to evaluate adenosine deaminase serum activity in patients with acute myocardial infarction, a prospective, observational study were done in 56 patients admitted to the central hospital emergency room with a diagnosis of acute myocardial infarction; 32 had elevation of ST segment in the electrocardiogram, of which 24 underwent thrombolysis therapy and 14 evolved a Q wave. Each patient was submitted to a clinical evaluation and serum activity of T troponin, creatine kinase, creatine kinase MB isoform of and adenosine deaminase were determined. Results illustrated that adenosine deaminase serum activity was 109.6 ± 8.34 nmol/mL, decreasing after treatment to 82.34 ±7.45 nmol/mL and 81.82 ± 9.40 nmol/mL at 24 and 72 hours, respectively, which it was significantly related in those patients that displayed no EST in electrocardiogram and received no thrombolytic treatment. In these patients adenosine deaminase activity was correlated with creatine kinase activity. In patients with elevation of ST segment (independently of developing a Q wave) receiving thrombolytic treatment, the adenosine deaminase serum activity remained elevated and unchanged. In conclusion: adenosine deaminase levels can be used as a molecular marker of the evolution in acute myocardial infarction patients receiving no thrombolytic therapy and presenting no changes in the ST segment |
| Disciplinas: | Medicina |
| Palabras clave: | Diagnóstico, Sistema cardiovascular, Síndrome coronario agudo, Infarto agudo del miocardio, Adenosina deaminasa, Marcadores moleculares, Creatina quinasa |
| Keyword: | Medicine, Cardiovascular system, Diagnosis, Acute coronary syndrome, Adenosine deaminase, Molecular markers, Creatine kinase |
| Texto completo: | Texto completo (Ver PDF) |
