| Revista: | Revista do Instituto de Medicina Tropical de Sao Paulo |
| Base de datos: | |
| Número de sistema: | 000547876 |
| ISSN: | 0036-4665 |
| Autores: | Ariza Ordoñez, Nicolás1 Gómez Sepúlveda, Valeria1 Pino Marín, Antonia2 Vargas Nieto, Lina Patricia1 Moreno León, Julián1 Millán Prada, Henry Augusto2 |
| Instituciones: | 1Fundación Cardioinfantil, Medicina Interna, Bogotá. Colombia 2Universidad del Rosario, Bogotá. Colombia |
| Año: | 2022 |
| Volumen: | 64 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Resumen en inglés | Leukocytoclastic vasculitis (LCV) is a small vessel vasculitis characterized by an inflammatory infiltrate composed of neutrophils with fibrinoid necrosis and “leukocytoclasia”, a term that refers to nuclei disintegration into fragments. LCV is related to multiple conditions including ANCA-associated vasculitis, cryoglobulinemia, IgA vasculitis, infectious and systemic diseases such as rheumatoid arthritis and systemic erythematous lupus (SLE) as well as infections and malignancy. We describe the clinical case of severe systemic vasculitis in a young male patient with secondary syphilis and HIV coinfection manifested by cutaneous and neurological involvement, as well as peripheral necrosis that requires bilateral lower limb amputation. The skin biopsy revealed histopathological changes compatible with endarteritis obliterans and LCV related to treponemal infection. This case highlights the plethora of clinical manifestations of treponemal infection and the diagnostic challenge this poses in current clinical practice. |
| Disciplinas: | Medicina, Biología |
| Palabras clave: | Microbiología, Virus |
| Keyword: | Microbiology, Virus |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
