| Revista: | Revista de saude publica |
| Base de datos: | |
| Número de sistema: | 000536019 |
| ISSN: | 0034-8910 |
| Autores: | Silva, Antônio Augusto Moura da1 Lima Neto, Lídio Gonçalves2 Azevedo, Conceição de Maria Pedrozo e Silva de4 Costa, Léa Márcia Melo da6 Bragança, Maylla Luanna Barbosa Martins7 Barros Filho, Allan Kardec Duailibe8 Wittlin, Bernardo Bastos5 Souza, Bruno Feres de10 Oliveira, Bruno Luciano Carneiro Alves de4 Carvalho, Carolina Abreu de11 Thomaz, Erika Barbara Abreu Fonseca1 Simões Neto, Eudes Alves9 Leite Júnior, Jamesson Ferreira13 Cosme, Lécia Maria Sousa Santos2 Campos, Marcos Adriano Garcia14 Queiroz, Rejane Christine de Sousa1 Costa, Sérgio Souza10 Carvalho, Vitória Abreu de14 Simões, Vanda Maria Ferreira1 Alves, Maria Teresa Seabra Soares de Brito e1 Santos, Alcione Miranda dos1 |
| Instituciones: | 1Universidade Federal do Maranhão, Departamento de Saúde Pública, São Luís. Brasil 2Laboratório Central do Maranhão, São Luís, MA. Brasil 3Universidade CEUMA, São Luís, MA. Brasil 4Universidade Federal do Maranhão, Departamento de Medicina I, São Luís. Brasil 5Saúde do Estado do Maranhão, Hospital Presidente Vargas, São Luís, MA. Brasil 6Saúde do Estado do Maranhão, São Luís, MA. Brasil 7Universidade Federal do Maranhão, Departamento de Ciências Fisiológicas, São Luís. Brasil 8Universidade Federal do Maranhão, Departamento de Engenharia Elétrica, São Luís. Brasil 9Universidade Federal do Maranhão, Hospital Universitário, São Luís. Brasil 10Universidade Federal do Maranhão, Departamento de Engenharia da Computação, São Luís. Brasil 11Universidade Federal do Maranhão, Curso de Medicina, Pinheiro. Brasil 12Secretaria Municipal de Saúde, São Luís, MA. Brasil 13Saúde do Estado do Maranhão, Centro de Informações Estratégicas de Vigilância em Saúde, São Luís, MA. Brasil 14Universidade Federal do Maranhão, Programa de Pós-Graduação em Saúde Coletiva, São Luís. Brasil |
| Año: | 2020 |
| Volumen: | 54 |
| País: | Brasil |
| Idioma: | Inglés |
| Resumen en inglés | OBJECTIVE: To estimate the seroprevalence of SARS-CoV-2 in the state of Maranhão, Brazil. METHODS: A population-based household survey was performed, from July 27, 2020 to August 8, 2020. The estimates considered clustering, stratification and non-response. Qualitative detection of IgM and IgG antibodies was performed in a fully-automated Elecsys® Anti-SARS-CoV-2 electrochemiluminescence immunoassay on the Cobas® e601 analyzer (Roche Diagnostics). RESULTS: In total, 3,156 individuals were interviewed. Seroprevalence of total antibodies against SARS-CoV-2 was 40.4% (95%CI 35.6-45.3). Population adherence to non-pharmaceutical interventions was higher at the beginning of the pandemic than in the last month. SARS-CoV-2 infection rates were significantly lower among mask wearers and among those who maintained social and physical distancing in the last month compared to their counterparts. Among the infected, 26.0% were asymptomatic. The infection fatality rate (IFR) was 0.14%, higher for men and older adults. The IFR based on excess deaths was 0.28%. The ratio of estimated infections to reported cases was 22.2. CONCLUSIONS: To the best of our knowledge, the seroprevalence of SARS-CoV-2 estimated in this population-based survey is one of the highest reported. The local herd immunity threshold may have been reached or might be reached soon. |
| Keyword: | Seroepidemiologic Studies, Coronavirus Infections, Immunity, Herd, Mortality |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
