Significant Rise in SARS-CoV-2 Reinfection Rate in Vaccinated Hospital Workers during the Omicron Wave: A Prospective Cohort Study



Título del documento: Significant Rise in SARS-CoV-2 Reinfection Rate in Vaccinated Hospital Workers during the Omicron Wave: A Prospective Cohort Study
Revista: Revista de investigación clínica
Base de datos: PERIÓDICA
Número de sistema: 000452956
ISSN: 0034-8376
Autores: 1
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Instituciones: 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México. México
Año:
Periodo: Jul-Ago
Volumen: 74
Número: 4
Paginación: 175-180
País: México
Idioma: Inglés
Tipo de documento: Nota breve o noticia
Enfoque: Aplicado, descriptivo
Resumen en inglés Relatively low SARS-CoV-2 reinfection rates have been reported in vaccinated individuals, but updates considering the Omicron variant are lacking. Objective: The objective of the study was to provide a current estimate of the SARS-CoV-2 reinfection rate in a highly immunized population. Methods: A prospective cohort of Mexican hospital workers was followed (March 2020-February 2022). Reinfection was defined as the occurrence of two or more episodes of COVID-19 separated by a period of ≥ 90 days without symptoms. The reinfection rate was calculated as the number of reinfection episodes per 100,000 persons per day. Results: A total of 3732 medical consultations were provided to 2700 workers, of whom 1388 (51.4%) were confirmed COVID-19 cases. A total of 73 reinfection cases were identified, of whom 71 (97.3%) had completed their primary vaccination series and 22 (30.1%) had had a booster dose before the second episode. The overall reinfection rate was 23.1 per 100,000 persons per day (as compared to a rate of 1.9 per 100,000 persons per day before the Omicron wave). Conclusions: The SARS-CoV-2 reinfection rate rose significantly during the Omicron wave despite a high primary vaccination coverage rate. Almost one-third of reinfected workers had a vaccine booster ≥ 14 days before the last COVID-19 episode
Disciplinas: Medicina
Palabras clave: Virus,
Neumología,
Hospitales,
COVID-19,
SARS-CoV-2,
Personal de salud,
Reinfección
Keyword: Virus,
Pneumology,
Hospitals,
COVID-19,
SARS-CoV-2,
Reinfection,
Health personnel
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