Revista: | Revista de investigación clínica |
Base de datos: | PERIÓDICA |
Número de sistema: | 000453178 |
ISSN: | 0034-8376 |
Autores: | Hormanstorfer, Macarena1 Ragusa, Martin A1 Poggio, Lucia1 Moreira Facundo, Jorge1 Orellana Villa, Zulma1 Bobrowski, Florencia A1 Martinez Serventi, Joaquin1 Piombi Adanza, Santiago N1 Enrique Barletta, Jose A2 Sisto, Alicia2 Delle Piane, Hugo1 Carrillo, Juan M1 Presas, Jose L1 Paulin, Francisco1 |
Instituciones: | 1Hospital Juan A. Fernández, División de Medicina Interna,, Buenos Aires. Argentina 2Hospital Juan A. Fernández, División de Enfermedades Infecciosas, Buenos Aires. Argentina |
Año: | 2021 |
Periodo: | Ene-Feb |
Volumen: | 73 |
Número: | 1 |
Paginación: | 52-58 |
País: | México |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Aplicado, descriptivo |
Resumen en inglés | Background: Severe pneumonia is the most common cause of intensive care unit (ICU) admission and death due to novel coronavirus (SARS-CoV-2) respiratory disease (COVID-19). Due to its rapid outbreak, units for the evaluation of febrile patients in the pre-hospital setting were created. Objective: The objective of the study was to develop a sensitive and simple tool to assess the risk of pneumonia in COVID-19 patients and thus select which patients would require a chest imaging study. Materials and Methods: We conducted a cross-sectional study in a cohort of individuals with suspected COVID-19 evaluated in a public academic healthcare center in Buenos Aires city. All adult patients with positive RT-PCR assay for SARS-COV2 between April 24 and May 19 of 2020 were included in the study. Pneumonia was defined as the presence of compatible signs and symptoms with imaging confirmation. Univariate and multivariate logistic regression was performed. A risk indicator score was developed. Results: One hundred and forty-eight patients were included, 71 (48%) received the diagnosis of pneumonia. The final clinical model included four variables: age ≥ 40 years, cough, absence of sore throat, and respiratory rate ≥ 22. To create the score, we assigned values to the variables according to their ORs: 2 points for respiratory rate ≥ 22 and 1 point to the other variables. The AUC of the ROC curve was 0.80 (CI 95% 0.73-0.86). A cutoff value of 2 showed a sensitivity of 95.7% and a specificity of 43.24%. Conclusion: This sensible score may improve the risk stratification of COVID-19 patients in the pre-hospital setting |
Disciplinas: | Medicina |
Palabras clave: | Neumología, Diagnóstico, COVID-19, SARS-CoV-2, Neumonía, Criterios diagnósticos |
Keyword: | Pneumology, Diagnosis, COVID-19, SARS-CoV-2, Pneumonia, Diagnostic criteria |
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