| Revista: | Revista de investigación clínica |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000453004 |
| ISSN: | 0034-8376 |
| Autores: | Piombi Adanza, Santiago N1 Baretto, María C1 Echaide, Flavia A1 Arias Mahiques, Josefina1 Carreras, Matías1 Hidalgo Fredez, Eliana1 Vignolo, Luciana M1 Parodi, Noel1 Domínguez Monclá, Tomás1 Carlos, Jimena del V1 Padula, María F1 Haedo, Santiago1 Sigman, Mariana1 Hermida, Laura1 Padilla, María J1 Paulin, Francisco1 |
| Instituciones: | 1Hospital Juan A. Fernández, División de Medicina Interna, Buenos Aires. Argentina |
| Año: | 2021 |
| Periodo: | Nov-Dic |
| Volumen: | 73 |
| Número: | 6 |
| Paginación: | 399-407 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Hospital bed saturation has been one of the problems to solve during the SARS-CoV-2 pandemic. However, not every patient who is admitted requires close monitoring or specific therapeutics. Mild cases could be managed in the outpatient setting. Objective: Our study aimed to analyze the accuracy of the oxygen saturation/respiratory rate (sat/RR) index, NEWS2, CURB65, and quick Sequential Organ Failure Assessment (qSOFA) scores to predict supplemental oxygen requirement and prolonged hospital stay in patients with mild coronavirus disease 2019 (COVID-19). Methods: A prospective cohort study in an academic medical center. We compared the values of these scores according to the occurrence or not of each outcome. When differences between groups were statistically significant, the discriminatory capacity of the score for that outcome was analyzed. Results: We included 271 patients. Of them, 11.07% required supplemental oxygen, showing significantly higher values of NEWS2 score and qSOFA score, and lower values of Sat/RR index. About 38% presented prolonged hospital stay, with significantly higher values of NEWS2 score and lower values of sat/RR index. The ROC curve area under the curve (AUC) of sat/RR index to discriminate the requirement of supplemental oxygen was 0.72 (CI 95% 0.61-0.84). The ROC curve of NEWS2 and qSOFA for the same outcome was 0.75 (95% [95% CI 0.65-0.85]) and 0.66 (95% CI 0.57-0.76), respectively. The ability of the Sat/RR index to discriminate the requirement of prolonged hospitalization showed an AUC of 0.67 (95% [95% CI 0.60-0.73]). The NEWS2 score showed an AUC of 0.63 (CI 95% 0.56-0.70) for the same outcome. Conclusions: sat/RR index and NEWS2 score have a good capacity to discriminate patients at risk of clinical worsening, being the Sat/RR index simpler and easier to calculate |
| Disciplinas: | Medicina |
| Palabras clave: | Neumología, Virus, Terapéutica y rehabilitación, COVID-19, SARS-CoV-2, Insuficiencia respiratoria, Prognosis, Neumonía |
| Keyword: | Pneumology, Virus, Therapeutics and rehabilitation, COVID-19, SARS-CoV-2, Pneumonia, Respiratory failure, Prognosis |
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