Comparative clinical and ultrasound study of egg-negative and egg-positive individuals from Schistosoma mansoni low morbidity endemic areas, and hospitalized patients with hepatosplenic disease



Título del documento: Comparative clinical and ultrasound study of egg-negative and egg-positive individuals from Schistosoma mansoni low morbidity endemic areas, and hospitalized patients with hepatosplenic disease
Revista: Revista da Sociedade Brasileira de Medicina Tropical
Base de datos: PERIÓDICA
Número de sistema: 000282676
ISSN: 0037-8682
Autores: 1
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3

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6
Instituciones: 1Santa Casa Hospital de Belo Horizonte, Belo Horizonte, Minas Gerais. Brasil
2Fundacao Instituto Oswaldo Cruz, Centro de Pesquisas Rene Rachou, Belo Horizonte, Minas Gerais. Brasil
3Universidade Vale do Rio Doce, Itajai, Santa Catarina. Brasil
4Universidade Federal de Minas Gerais, Escola de Enfermagem, Belo Horizonte, Minas Gerais. Brasil
5The George Washington University, Medical Center, Washington, Distrito de Columbia. Estados Unidos de América
6Faculdade de Medicina do Triangulo Mineiro, Uberaba, Minas Gerais. Brasil
Año:
Periodo: Ene-Feb
Volumen: 38
Número: 1
Paginación: 33-37
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico
Resumen en inglés Two hundred and twenty three subjects from a Schistosoma mansoni low morbidity endemic area and nine hospitalized hepatosplenic patients were submitted to stool test and clinical examination and abdomen ultrasound assessments. According to stool examination and ultrasound results, they were grouped as follows: G1 - 63 Schistosoma mansoni egg-negative individuals; G2 - 141 egg-positive patients and without evidence of periportal fibrosis; G3 - 19 egg-positive patients with periportal echogenicity (3-6mm); and G4 - 9 hepatosplenic patients with periportal echogenicity (> 6mm). Hepatomegaly detected by physical examination of the abdomen evaluated in the midclavicular line was verified in G1, G2 and G3, respectively, in 11.1, 12.1 and 26.3%. In G1, G2 and G3, periportal thickening occurred only in schistosomal patients (8.5%). Mild pathological alterations in patients that cannot yet be detected by clinical examination were detectable in the liver by ultrasound and can be due to fibrosis. The degree of mild periportal fibrosis was diminished in 57.9% of patients 12 months after treatment of schistosomiasis with oxamniquine. At ultrasonography, the mean liver left lobe measurement of G3 was larger than that of G1, and that of G4 larger than that of G1 and G2. The mean size of the spleen of G4 was significantly larger than that of the other three groups, and that of G3 larger than that of G1 and G2
Disciplinas: Biología,
Medicina
Palabras clave: Parasitología,
Salud pública,
Esquistosomiasis,
Ultra-sonografia,
Fibrosis,
Schistosoma mansoni
Keyword: Biology,
Medicine,
Parasitology,
Public health,
Ultrasonography,
Fibrosis,
Schistosomiasis,
Schistosoma mansoni
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